Murawska Baptista Aleksandra, Alok Akankcha, Libertin Claudia
Mayo Clinic Alix School of Medicine, Department of Internal Medicine, 4500 San Pablo Rd S, Jacksonville, FL 32224, USA.
Mayo Clinic, 4500 San Pablo Rd S, Jacksonville, FL 32224, USA.
IDCases. 2022 Mar 5;28:e01467. doi: 10.1016/j.idcr.2022.e01467. eCollection 2022.
Since the beginning of the COVID-19 pandemic, great hesitancies regarding the COVID-19 immunization have existed. The most striking adverse events reported include thrombosis with thrombocytopenia syndrome (TTS), myocarditis, and Guillain Barre Syndrome (GBS). Post-vaccination GBS is known since the time of Influenza vaccination, but several cases of GBS have also been reported in the current COVID-19 vaccination era. As a result, our patient with a history of GBS post-Influenza vaccination, went unvaccinated for SARS-CoV-2, due to fear of GBS re-activation. Consequently, he contracted COVID-19 pneumonitis complicated with deep venous thrombosis, requiring a prolonged hospitalization. Weighing the risks and benefits of vaccination to COVID-19 is difficult, especially for people with a previous history of GBS related to Influenza vaccination. We reviewed and analyzed the reported cases of GBS temporary related to COVID-19 vaccination to determine the safety of their administration in those with a history of GBS.
自新冠疫情开始以来，人们对新冠疫苗接种存在很大的犹豫。报告的最显著不良事件包括血栓性血小板减少综合征（TTS）、心肌炎和吉兰-巴雷综合征（GBS）。接种疫苗后发生的GBS自流感疫苗接种时就已为人所知，但在当前的新冠疫苗接种时代也报告了几例GBS病例。因此，我们这位有流感疫苗接种后发生GBS病史的患者，由于担心GBS复发，未接种新冠病毒疫苗。结果，他感染了新冠肺炎并并发深静脉血栓形成，需要长期住院治疗。权衡新冠疫苗接种的风险和益处很困难，尤其是对于有流感疫苗接种相关GBS病史的人。我们回顾并分析了报告的与新冠疫苗接种临时相关的GBS病例，以确定在有GBS病史的人群中接种疫苗的安全性。
