Gao Dengyu, Sun Lu, Wang Ning, Shi Yubo, Song Jianli, Liu Xiaoying, Yang Qiyao, Su Zhenbo
Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, China.
Department of Anesthesiology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Front Surg. 2022 Feb 24;9:792697. doi: 10.3389/fsurg.2022.792697. eCollection 2022.
This study aimed to evaluate the impact of patients' positioning before and after intubation with mechanical ventilation, and after extubation on the lung function and blood oxygenation of patients with morbid obesity, who had a laparoscopic sleeve gastrectomy.
Patients with morbid obesity (BMI ≥ 30 kg/m, ASA I - II grade) who underwent laparoscopic sleeve gastrectomy at our hospital from June 2018 to January 2019 were enrolled in this prospective study. Before intubation, after intubation with mechanical ventilation, and after extubation, arterial blood was collected for blood oxygenation and gas analysis after posturing the patients at supine position or 30° reverse Trendelenburg position (30°-RTP).
A total of 15 patients with morbid obesity were enrolled in this self-compared study. Pulmonary shunt (Qs/Qt) after extubation was significantly lower at 30°-RTP (18.82 ± 3.60%) compared to that at supine position (17.13 ± 3.10%, < 0.01). Patients' static lung compliance (Cstat), during mechanical ventilation, was significantly improved at 30°-RTP (36.8 ± 6.7) compared to that of those in a supine position (33.8 ± 7.3, < 0.05). The PaO and oxygen index (OI) before and after intubation with mechanical ventilation were significantly higher at 30°-RTP compared to that at supine position, and in contrast, the PO before and after intubation with mechanical ventilation was significantly reduced at 30°-RTP compared to that at supine position.
During and after laparoscopic sleeve gastrectomy, patients with morbid obesity had improved lung function, reduced pulmonary shunt, reduced PO difference, and increased PaO and oxygen index at 30°-RTP compared to that supine position.
本研究旨在评估病态肥胖患者在腹腔镜袖状胃切除术中机械通气插管前后及拔管后不同体位对其肺功能和血氧饱和度的影响。
选取2018年6月至2019年1月在我院接受腹腔镜袖状胃切除术的病态肥胖患者(BMI≥30kg/m²,ASA I-II级)纳入本前瞻性研究。在患者仰卧位或30°头高足低位(30°-RTP)体位下,于插管前、机械通气插管后及拔管后采集动脉血进行血氧饱和度和血气分析。
本自身对照研究共纳入15例病态肥胖患者。与仰卧位相比,拔管后30°-RTP时肺内分流(Qs/Qt)显著降低(18.82±3.60% vs 17.13±3.10%,P<0.01)。机械通气期间,30°-RTP时患者的静态肺顺应性(Cstat)较仰卧位显著改善(36.8±6.7 vs 33.8±7.3,P<0.05)。与仰卧位相比,机械通气插管前后30°-RTP时的PaO₂和氧合指数(OI)显著升高,相反,机械通气插管前后30°-RTP时的PCO₂显著降低。
在腹腔镜袖状胃切除术期间及术后,与仰卧位相比,病态肥胖患者在30°-RTP时肺功能改善,肺内分流减少,PCO₂差值减小,PaO₂和氧合指数升高。