粘质沙雷氏菌临床和环境分离株潜在毒力因子的调查

A survey of potential virulence factors in clinical and environmental isolates of Serratia marcescens.

作者信息

Franczek S P, Williams R P, Hull S I

出版信息

J Med Microbiol. 1986 Sep;22(2):151-6. doi: 10.1099/00222615-22-2-151.

Abstract

One hundred and forty seven isolates of Serratia marcescens were collected from diverse clinical and environmental sources in south-east Texas. Natural isolates were compared with hospital strains for the occurrence of 12 potential virulence determinants. Their overall frequency was as follows: haemolytic activity 48%; lecithinase 95%; lipase 95%; motility 99%; pigmentation 24%; plasmid carriage 46%; proteolytic activity 98%; siderophore activity 99%; urease activity 5%; mannose-sensitive haemagglutination 96%; mannose-resistant haemagglutination 61%; and mannose-resistant type-K haemagglutination (MR/K-HA) 68%. Clinical strains demonstrated a significantly higher occurrence of MR/K-HA (p less than 0.001) and non-pigmentation (p less than 0.01) than environmental isolates.

摘要

从得克萨斯州东南部不同临床和环境来源收集了147株粘质沙雷氏菌分离株。将自然分离株与医院菌株比较12种潜在毒力决定因素的出现情况。它们的总体频率如下：溶血活性48%；卵磷脂酶95%；脂肪酶95%；运动性99%；色素沉着24%；质粒携带46%；蛋白水解活性98%；铁载体活性99%；脲酶活性5%；甘露糖敏感血凝96%；甘露糖抗性血凝61%；以及甘露糖抗性K型血凝（MR/K-HA）68%。临床菌株显示MR/K-HA（p小于0.001）和无色素沉着（p小于0.01）的发生率显著高于环境分离株。