The Outpatient Department, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Institute of Tropical Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Drug Dev Ind Pharm. 2021 Nov;47(11):1693-1699. doi: 10.1080/03639045.2022.2053984. Epub 2022 Mar 29.
The COVID-19 is caused by the SARS-CoV-2, which is extremely infectious. Numerous virologist suggestions and guidelines advised using P2/N95 masks, gloves, goggles, face-shields, and frocks or gowns as routine specific protective tools during airway management to protect healthcare personnel from infection (PPE). However, numerous imitation research has indicated that conventional PPE cannot adequately protect healthcare personnel. Since then, numerous firms and healthcare professionals have created their personal reformed devices 'aerosol containment devices' (ACD). Their usage has expanded throughout the world without being properly evaluated for usefulness, efficacy, or safety. The practice of 'ACD' has been shown to make tracheal intubation (TI) more problematic in several simulated tests. Furthermore, the device should limit the transmission of droplets from a patient; however, it might put healthcare personnel at danger of being exposed to greater levels of viral aerosols. Consequently, the existing state of information suggests that 'ACD' deprived of a vacuum mechanism can simply protect healthcare personnel against viral transmission to a limited extent. We search various databases for the literature with keywords 'COVID-19,' 'aerosol box,' 'aerosol contaminations,' and 'droplet contaminations.' The current review focused on the aerosol box from various perspectives, including their mechanism, optimum time of use, the spread of aerosol control, current gaps, and future perspective for bridging those gaps.
新型冠状病毒（SARS-CoV-2）引发的 COVID-19 具有极强的传染性。许多病毒学家建议并指导在气道管理期间使用 P2/N95 口罩、手套、护目镜、面罩和长袍或手术服等常规特定防护工具，以保护医护人员免受感染（PPE）。然而，大量的模拟研究表明，常规 PPE 无法充分保护医护人员。此后，许多公司和医护专业人员制造了他们自己改装的“气溶胶隔离装置”（ACD）。这些设备在没有经过充分评估其有效性、功效或安全性的情况下就在全球范围内得到了广泛应用。多项模拟测试表明，ACD 的使用使气管插管（TI）变得更加困难。此外，该设备应该限制患者飞沫的传播；然而，它可能会使医护人员面临更大程度暴露于病毒气溶胶的风险。因此，现有信息表明，没有真空机制的 ACD 只能在一定程度上保护医护人员免受病毒传播。我们使用“COVID-19”、“气溶胶盒”、“气溶胶污染”和“飞沫污染”等关键词在各种数据库中搜索相关文献。本综述从多个角度关注了气溶胶盒，包括其作用机制、最佳使用时间、气溶胶控制的传播、当前的差距以及未来弥合这些差距的前景。
