CEACAM1 是一种新型的与培养兼容的长期重建造血干细胞表面标志物。
CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.
机构信息
Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer.
Cell Signalling and Proteomics Research Unit, Institute for Research in Immunology and Cancer, and.
出版信息
Blood Adv. 2022 Jun 28;6(12):3626-3631. doi: 10.1182/bloodadvances.2021006835.
Abstract
CEACAM1 is a novel cell surface marker of ex vivo expanded LT-HSCs. Sorting umbilical cord blood cells based on CEACAM1 and known HSC marker expression allows purification of LT-HSCs with improved purity.
摘要
CEACAM1 是一种新型的体外扩增 LT-HSCs 细胞表面标志物。基于 CEACAM1 和已知的 HSC 标志物表达对脐血细胞进行分选，可提高 LT-HSCs 的纯度。
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