切除高级别胶质瘤后植入硬膜下聚酯氨交连体作为隔置物以减少脑膜-脑粘连。
Reducing meningo-cerebral adhesions by implanting an interpositional subdural polyesterurethane graft after high-grade glioma resection.
机构信息
Department of Neurosurgery, Kwong Wah Hospital, Hong Kong, Hong Kong.
Department of Anatomical Pathology, Kwong Wah Hospital, Hong Kong, Hong Kong.
出版信息
Acta Neurochir (Wien). 2022 Aug;164(8):2057-2062. doi: 10.1007/s00701-022-05163-4. Epub 2022 Mar 14.
BACKGROUND
Meningo-cerebral adhesions are frequently encountered during recurrent high-grade glioma resections. Adhesiolysis not only lengthens operation times, but can also induce focal cortical tissue injury that could affect overall survival.
METHODS
Immediately after the primary resection of a high-grade glioma, a polyesterurethane interpositional graft was implanted in the subdural space covering the entire exposed cortex as well as beneath the dural suture line. No postoperative complications were documented. All patients received adjuvant radiotherapy. Upon repeat resection for focal tumor recurrence, the graft was shown to effectively reduce meningo-cerebral adhesion development.
CONCLUSION
The implantation of a synthetic subdural graft is a safe and effective method for preventing meningo-cerebral adhesions.
背景
复发性高级别胶质瘤切除术中经常会遇到脑膜-脑粘连。松解粘连不仅会延长手术时间，还可能导致局部皮质组织损伤，从而影响整体存活率。
方法
在高级别脑胶质瘤的初次切除后，将聚酯氨酯间置移植物植入覆盖整个暴露皮质以及硬脑膜缝线下方的硬脑膜下间隙。没有记录到术后并发症。所有患者均接受辅助放疗。在重复切除局部肿瘤复发时，移植物显示出有效降低脑膜-脑粘连发展的效果。
结论
植入合成硬脑膜下移植物是预防脑膜-脑粘连的一种安全有效的方法。
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