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32 只连续犬经静脉应用 Amplatzer 血管塞 II 封堵动脉导管未闭。

The use of Amplatzer vascular plug II in 32 consecutive dogs for transvenous occlusion of patent ductus arteriosus.

机构信息

Southern Counties Veterinary Specialists, 6 Forest Corner Farm, Hampshire, BH24 3JW, UK.

Southern Counties Veterinary Specialists, 6 Forest Corner Farm, Hampshire, BH24 3JW, UK.

出版信息

J Vet Cardiol. 2022 Jun;41:88-98. doi: 10.1016/j.jvc.2021.05.005. Epub 2021 May 29.

Abstract

OBJECTIVES

To describe the use of the Amplatzer vascular plug II (AVPII) for transvenous occlusion of patent ductus arteriosus in a non-selective population of dogs, with a focus on the surgical technique, short term outcome and associated complications.

ANIMALS, MATERIALS AND METHODS: Retrospective study. Records of thirty-two consecutive dogs treated for a left-to-right shunting patent ductus arteriosus with the AVPII were reviewed.

RESULTS

Ductal occlusion with an AVPII occlusion device was attempted in 32 dogs weighing 1.1-53.8 kg. Transvenous occlusion was successful in 30 dogs. One dog required a transarterial approach for occlusion. One dog died during catheterisation of the right heart but prior to transductal catheterisation. Mean ductal ampulla diameter was 7.9 mm (range, 4.1-15.4 mm) and median size of deployed devices was 10 mm (range 4-20 mm). Mean device to ampulla ratio was 1.34 ± 0.15. Device was positioned in situ with no residual flow on follow-up echocardiographic assessment (> one month) in all dogs where deployment was attempted. Occlusion success rate was 96.9% and mortality rate was 3.1%. Four dogs (13.3%) demonstrated minor complications, with none having long-term significance.

CONCLUSIONS

The use of AVPII device via a transvenous approach is a feasible and effective method for occlusion of a left-to-right shunting patent ductus arteriosus in dogs of a wide range of weight. The method described may complement existing catheter-based occlusion methods.

摘要

目的

描述使用 Amplatzer 血管塞 II(AVPI)对非选择性犬群体的动脉导管未闭进行经静脉闭塞,重点介绍手术技术、短期结果和相关并发症。

动物、材料和方法:回顾性研究。对 32 只因左向右分流性动脉导管未闭而接受 AVPII 治疗的连续犬的记录进行了回顾。

结果

在 32 只体重 1.1-53.8kg 的犬中尝试使用 AVPII 闭塞装置闭塞导管。30 只犬经静脉闭塞成功。1 只犬需要经动脉入路进行闭塞。1 只犬在导管插入右心但在经导管插入前死亡。平均导管壶腹直径为 7.9mm(范围 4.1-15.4mm),放置的装置中位数大小为 10mm(范围 4-20mm)。装置与壶腹的比值平均为 1.34±0.15。在所有尝试放置装置的犬中,装置在原位定位,在随访超声心动图评估(>1 个月)时无残余血流。闭塞成功率为 96.9%,死亡率为 3.1%。4 只犬(13.3%)出现轻微并发症,但无长期意义。

结论

使用 AVPII 装置经静脉入路是一种可行且有效的方法,可用于闭塞各种体重犬的左向右分流性动脉导管未闭。所描述的方法可能补充现有的基于导管的闭塞方法。

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