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养心方联合常规西药治疗冠心病心绞痛的疗效。

Efficacy of Yangxin Recipe in Combination with Conventional Western Medicine in Treatment of Angina Pectoris of Coronary Heart Disease.

机构信息

Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.

Department of Internal Medicine-Cardiovascular, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.

出版信息

Clin Appl Thromb Hemost. 2022 Jan-Dec;28:10760296221076152. doi: 10.1177/10760296221076152.

DOI:10.1177/10760296221076152
PMID:35287480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8928372/
Abstract

OBJECTIVE

To study the efficacy of Yangxin Recipe (YXR) in patients with stable angina pectoris of coronary heart disease and its impacts on coronary CT angiography.

METHODS

A total of 78 patients with coronary heart disease and angina pectoris were randomly divided into a control group (n = 39) and a YXR group (n = 39). The control group adopted conventional Western medicine while the YXR group received conventional western medicine + oral administration of YXR. After six months of continuous treatment, the clinical efficacy, traditional Chinese medicine (TCM) syndrome scores, Pittsburgh Sleep Quality Index (PSQI), and the level of coronary CT vascular stenosis were observed.

RESULTS

After treatment, the total effective rate of YXR was 92.31%, which was higher than ( < 0.01) that of the western medicine control group. The total score of TCM syndromes in the YXR group was (14.44 ± 9.87), which was significantly lower than ( < 0.001) that in the simple western medicine control group (22.44 ± 13.87). The degree of coronary stenosis in the YXR group decreased to (49.87 ± 7.82) %, which was significantly lower than ( < 0.001) that in the western medicine control group (57.05 ± 9.92) %.

CONCLUSION

The efficacy of YXR + conventional western medicine in treating coronary heart disease and angina pectoris is significantly improved compared with the simple conventional western medicine.

摘要

目的

研究养心方（YXR）对冠心病稳定型心绞痛患者的疗效及其对冠状动脉 CT 血管造影的影响。

方法

将 78 例冠心病心绞痛患者随机分为对照组（n=39）和 YXR 组（n=39）。对照组采用常规西药治疗，YXR 组采用常规西药+口服 YXR。连续治疗 6 个月后，观察临床疗效、中医证候评分、匹兹堡睡眠质量指数（PSQI）和冠状动脉 CT 血管狭窄程度。

结果

治疗后，YXR 的总有效率为 92.31%，明显高于（<0.01）单纯西药对照组。YXR 组中医证候总积分（14.44±9.87）明显低于（<0.001）单纯西药对照组（22.44±13.87）。YXR 组的冠状动脉狭窄程度下降至（49.87±7.82）%，明显低于（<0.001）单纯西药对照组（57.05±9.92）%。

结论

与单纯常规西药相比，YXR+常规西药治疗冠心病心绞痛的疗效明显提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/5888b464e8d0/10.1177_10760296221076152-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/5ea9df13aaa5/10.1177_10760296221076152-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/ca51f32b3f7c/10.1177_10760296221076152-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/5888b464e8d0/10.1177_10760296221076152-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/5ea9df13aaa5/10.1177_10760296221076152-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/ca51f32b3f7c/10.1177_10760296221076152-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f349/8928372/5888b464e8d0/10.1177_10760296221076152-fig3.jpg

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