Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Division of Pediatric Orthopaedic Surgery, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.
Cartilage. 2022 Jan-Mar;13(1):19476035221085142. doi: 10.1177/19476035221085142.
To investigate compositional changes in the distal femoral condylar cartilage (FCC) of children and young adults with and without discoid meniscus by T2 relaxation time mapping.
We retrospectively reviewed knee magnetic resonance images including sagittal T2 maps of distal FCC performed in patients with or without discoid meniscus. Combined meniscal pathology such as degeneration or tears was also reviewed. Regions of interest were selected, and T2 relaxation time profiles were generated according to medial and lateral and FCC and according to weight-bearing and non-weight-bearing FCC. Nonparametric comparison tests using median values were performed.
Seventy-nine knees from 73 patients (2-20 years) including 45 knees with lateral discoid meniscus (discoid group) were studied. T2 values of FCC showed negative correlation with age in both the discoid and nondiscoid groups ( < 0.01), except for medial weight-bearing FCC. In the discoid group, T2 relaxation times of lateral weight-bearing FCC (median, 46.5 ms) were lower than those of lateral non-weight-bearing (median, 53.2 ms; < 0.001) and medial weight-bearing (median, 50.5 ms; = 0.012) FCC. Lateral weight-bearing FCC also showed lower T2 values than other areas in patients with meniscal pathology in the discoid group. However, T2 relaxation times did not differ between the discoid and nondiscoid groups in patients without meniscal pathology.
Children and young adults with discoid meniscus have lower T2 relaxation times in lateral weight-bearing FCC compared with non-weight-bearing or medial FCC, suggesting compositional changes have occurred in these patients.
通过 T2 弛豫时间图研究有和无盘状半月板的儿童和青少年股骨远端髁间窝软骨（FCC）的成分变化。
我们回顾性地分析了包括股骨远端 FCC 矢状 T2 图的膝关节磁共振成像，这些图像来自于有或无盘状半月板的患者。还回顾了包括退变或撕裂在内的合并半月板病变。选择感兴趣区域，并根据内侧和外侧以及 FCC 以及负重和非负重 FCC 生成 T2 弛豫时间曲线。使用中位数进行了非参数比较检验。
73 名患者（2-20 岁）的 79 个膝关节包括 45 个外侧盘状半月板（盘状组）。FCC 的 T2 值与盘状和非盘状组的年龄均呈负相关（ < 0.01），除了内侧负重 FCC 外。在盘状组中，外侧负重 FCC（中位数 46.5ms）的 T2 弛豫时间低于外侧非负重（中位数 53.2ms； < 0.001）和内侧负重（中位数 50.5ms； = 0.012）FCC。在盘状组中，有半月板病变的患者中，外侧负重 FCC 的 T2 值也低于其他区域。然而，在无半月板病变的患者中，盘状和非盘状组之间的 T2 弛豫时间没有差异。
与非负重或内侧 FCC 相比，有盘状半月板的儿童和青少年外侧负重 FCC 的 T2 弛豫时间较低，提示这些患者的成分发生了变化。
