Department of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China.
The First Affiliated Hospital of Zhejiang University, Hangzhou, 310003, Zhejiang, China.
BMC Med Educ. 2022 Mar 14;22(1):173. doi: 10.1186/s12909-022-03234-9.
Patients with sepsis have a high mortality rate, accumulated evidences suggest that an optimal antibiotic administration strategy based on pharmacokinetics/pharmacodynamics (PK/PD) can improve the prognosis of septic patients. Therefore, we assessed Chinese intensive care unit (ICU) physicians' knowledge about PK/PD.
In December 2019, we designed a questionnaire focused on Chinese ICU physicians' knowledge about PK/PD and collected the questionnaires after 3 months. The questionnaire was distributed via e-mail and WeChat, and was distributed to ICU doctors in 31 administrative regions of China except Hong Kong, Macao and Taiwan. The passing score was corrected by the Angoff method, and the ICU physicians' knowledge about PK/PD was analysed accordingly.
We received a total of 1,309 questionnaires and retained 1,240 valid questionnaires. The passing score was 90.8, and the overall pass rate was 56.94%. The pass rate for tertiary and secondary hospitals was 59.07% and 37.19%, respectively. ICU physicians with less than 5 years of work experience and resident physician accounted for the highest pass rate, while those with between 5 to 10 years of work experience and attending accounted for the lowest pass rate. The majority of participants in the Chinese Critical Care Certified Course (5C) were from Jiangsu and Henan provinces, and they had the highest average scores (125.8 and 126.5, respectively). For Beijing and Shanghai, the average score was only 79.4 and 90.9, respectively.
Chinese ICU physicians' knowledge about PK/PD is unsatisfactory. Therefore, it is essential to strengthen ICU physicians' knowledge about PK/PD.
脓毒症患者的死亡率很高，大量证据表明，基于药代动力学/药效学（PK/PD）的最佳抗生素给药策略可以改善脓毒症患者的预后。因此，我们评估了中国重症监护病房（ICU）医生对 PK/PD 的了解。
2019 年 12 月，我们设计了一份专注于中国 ICU 医生对 PK/PD 了解的问卷，并在 3 个月后收集了问卷。问卷通过电子邮件和微信分发，分发给中国除香港、澳门和台湾以外的 31 个行政区域的 ICU 医生。及格分数采用 Angoff 法校正，并据此分析 ICU 医生对 PK/PD 的了解。
我们共收到 1309 份问卷，保留了 1240 份有效问卷。及格分数为 90.8，总及格率为 56.94%。三级和二级医院的及格率分别为 59.07%和 37.19%。工作经验不足 5 年和住院医师的及格率最高，而工作经验 5-10 年和主治医生的及格率最低。参加中国重症医学认证课程（5C）的大多数人来自江苏和河南省，他们的平均得分最高（分别为 125.8 和 126.5）。对于北京和上海，平均得分仅为 79.4 和 90.9。
中国 ICU 医生对 PK/PD 的了解并不令人满意。因此，加强 ICU 医生对 PK/PD 的了解至关重要。
