College of Food Science, Southwest University, Chongqing 400715, PR China; Chongqing Key Laboratory of Chinese Medicine & Health Science, Chongqing Academy of Chinese Materia Medica, Chongqing 400065, PR China.
Chongqing Institute for Food and Drug Control, Chongqing 401121, PR China.
Carbohydr Polym. 2022 May 15;284:119182. doi: 10.1016/j.carbpol.2022.119182. Epub 2022 Jan 29.
By reviewing the published literatures, especially from 2016 to 2021, preparative approaches of hydrophobically modified polysaccharides (HMP), mechanisms underlying their self-aggregation, and food applications of HMP and their self-aggregates, as well as perspectives and challenges, were discussed. Up to ten methods were reported for HMP preparations from various polysaccharides with different hydrophobic substituents. In contrast to their unmodified-counterparts, HMP displayed stronger assembling tendencies to form multimolecular self-aggregates. Different types of self-aggregates including micelles, polymersomes, hydrogels, and reverse-micelles, were analyzed and they were depended on structural parameters of HMP and their environmental conditions. Basically, their formation was mainly driven by intermolecular interactions of HMP such as hydrophobic, hydrogen-bonding, and electrostatic interactions. HMP and their self-aggregates could be used in food fields in different ways, such as carriers for targeted-delivery, controlled-release and stabilization of bioactive compounds, stabilizers for emulsions, and functional ingredients for antimicrobial films, improving nutrition and properties of foods.
通过查阅已发表的文献，特别是 2016 年至 2021 年的文献，讨论了疏水性改性多糖（HMP）的制备方法、其自组装的机制、HMP 及其自组装体在食品中的应用，以及前景和挑战。从各种具有不同疏水性取代基的多糖中报道了多达 10 种 HMP 制备方法。与未改性的多糖相比，HMP 表现出更强的组装倾向，形成多分子自组装体。不同类型的自组装体，包括胶束、聚合物囊泡、水凝胶和反胶束，进行了分析，它们取决于 HMP 的结构参数及其环境条件。基本上，它们的形成主要是由 HMP 之间的分子间相互作用驱动的，如疏水、氢键和静电相互作用。HMP 及其自组装体可以以不同的方式应用于食品领域，例如作为靶向递送、生物活性化合物的控制释放和稳定的载体，乳液的稳定剂，以及抗菌薄膜的功能性成分，以改善食品的营养和性质。
