Pedersen E B, Danielsen H, Fjeldborg O, Kornerup H J, Madsen B
Nephron. 1986;44 Suppl 1:29-31. doi: 10.1159/000184042.
Fourteen patients with severe hypertension and renal artery stenosis were treated surgically. One patient died 4 days after surgery due to a cerebral thrombosis. The other 13 patients were followed for 18-24 months. Five were considered cured since the diastolic blood pressure (DBP) was less than or equal to 90 mm Hg without therapy. Five were improved since DBP was less than or equal to 100 mm Hg during treatment with only one or two antihypertensive agents. There were unchanged. Renal vein renin ratio (RVRR) was greater than or equal to 1.5 either before or after furosemide in all patients who were cured or improved and less than or equal to 1.5 in 2 of 3 who were unchanged. It can be concluded that surgical treatment cured or improved 77% of the patients, and that a RVRR greater than or equal to 1.5 is a good predictor of the blood pressure lowering effect of surgery.
14例重度高血压合并肾动脉狭窄患者接受了手术治疗。1例患者术后4天因脑血栓形成死亡。其余13例患者随访18 - 24个月。5例患者被认为治愈,因为其舒张压(DBP)在未接受治疗的情况下小于或等于90 mmHg。5例患者病情改善,因为其DBP在仅使用一两种抗高血压药物治疗期间小于或等于100 mmHg。有3例患者病情未改变。所有治愈或改善的患者在使用速尿前后肾静脉肾素比值(RVRR)均大于或等于1.5,而3例病情未改变的患者中有2例RVRR小于或等于1.5。可以得出结论,手术治疗使77%的患者治愈或改善,且RVRR大于或等于1.5是手术降压效果的良好预测指标。