Allelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), School of Science, University of Cádiz, Campus CEIA3, C/ República Saharaui, 7, Puerto Real, Cádiz 11510, Spain.
Departamento de Ciencia de Los Materiales e Ingeniería Metalúrgica y Química Inorgánica, Facultad de Ciencias, Universidad de Cádiz, C/ República Saharaui, 7, Puerto Real, Cádiz 11510, Spain.
J Agric Food Chem. 2022 Mar 30;70(12):3644-3653. doi: 10.1021/acs.jafc.1c07806. Epub 2022 Mar 15.
The encapsulation of bioactive natural products has emerged as a relevant tool for modifying the poor physicochemical properties often exhibited by agrochemicals. In this regard, natural guaiane-type sesquiterpene lactones isolated from L. have been encapsulated in a core/shell nanotube@agrochemical system. Monitoring of the F and O signals in marked sesquiterpenes confirmed that the compound is present in the nanotube cavity. These structures were characterized using scanning transmission electron microscopy-X-ray energy-dispersive spectrometry techniques, which revealed the spatial layout relationship and confirmed encapsulation of the sesquiterpene lactone derivative. In addition, biological studies were performed with aguerin B (), cynaropicrin (), and grosheimin () on the inhibition of germination, roots, and shoots in weeds ( L., L., and L.). Encapsulation of lactones in nanotubes gives better results than those for the nonencapsulated compounds, thereby reinforcing the application of fully organic nanotubes for the sustainable use of agrochemicals in the future.
将具有生物活性的天然产物包封起来，已成为一种改变农用化学品通常表现出的较差物理化学性质的有效手段。在这方面，从 L. 中分离出的天然愈创木烷型倍半萜内酯已被包封在核/壳纳米管@农用化学品体系中。对标记的倍半萜中 F 和 O 信号的监测证实，该化合物存在于纳米管腔中。使用扫描透射电子显微镜- X 射线能量色散光谱技术对这些结构进行了表征，该技术揭示了空间布局关系，并证实了倍半萜内酯衍生物的包封。此外，还对 aguerin B ()、cynaropicrin ()和 grosheimin ()进行了生物研究，以研究其对杂草（ L.、 L. 和 L.）的发芽、根和芽的抑制作用。内酯在纳米管中的包封比非包封化合物的效果更好，从而加强了全有机纳米管在未来可持续使用农用化学品方面的应用。
