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胸大肌皮瓣联合腹直肌鞘筋膜皮瓣在胸骨感染重建中的疗效和安全性。

Efficacy and safety of pectoralis muscle flap combined rectus abdominis muscle sheath fasciocutaneous flap for reconstruction of sternal infection.

机构信息

Division of Plastic Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei City, Taiwan.

Department of Medicine, MacKay Medical College, New Taipei, Taiwan.

出版信息

Int Wound J. 2022 Nov;19(7):1829-1837. doi: 10.1111/iwj.13788. Epub 2022 Mar 15.

DOI:10.1111/iwj.13788
PMID:35289489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9615267/
Abstract

Few studies have assessed the efficacy and safety of reconstruction of sternal infection using a pectoralis muscle flap combined with a rectus abdominis muscle (RAM) sheath fasciocutaneous flap. We report here our experience with this procedure to reconstruct the sternal defect in patients (n = 46) with a deep sternal wound infection (DSWI) after cardiac surgery. After wound reconstruction, the proportion of prolonged mechanical ventilation use and intensive care unit (ICU) stay were 17.4% (n = 8) and 21.7% (n = 10), respectively. The 30-day all-cause mortality was 15.2%; recurrence rate was 17.4%; postoperative complications were 15.2%; and median hospital stay was 31 (0-157) days. Multivariate logistic regression analysis revealed that hypertension (β = 21.32, 95%CI 4.955-37.68, P = .014), drainage-tube use (β = 0.944, 95%CI 0.273-1.614, P = .008), and prolonged intensive care unit stay (β = 53.65, 95%CI 31.353-75.938, P < .001) were significantly correlated with hospital stay. In conclusion, a procedure including surgical debridement, sternal reconstruction with bilateral PM and RAM sheath flap, long-term antibiotics, and adequate drainage is a beneficial technique in the reconstruction of deep sternal wound infection after cardiac surgery. Duration of drainage tube use may be as an index for a hospital stay or wound healing.

摘要

少数研究评估了使用胸大肌皮瓣联合腹直肌鞘筋膜皮瓣重建胸骨感染的疗效和安全性。我们在此报告我们使用该方法重建心脏手术后发生深部胸骨伤口感染(DSWI)的患者(n=46)胸骨缺损的经验。在进行伤口重建后,需要长时间机械通气和入住重症监护病房(ICU)的比例分别为 17.4%(n=8)和 21.7%(n=10)。30 天全因死亡率为 15.2%;复发率为 17.4%;术后并发症发生率为 15.2%;中位住院时间为 31(0-157)天。多变量逻辑回归分析显示,高血压(β=21.32,95%CI 4.955-37.68,P=0.014)、引流管使用(β=0.944,95%CI 0.273-1.614,P=0.008)和 ICU 入住时间延长(β=53.65,95%CI 31.353-75.938,P < 0.001)与住院时间显著相关。总之,包括手术清创、双侧胸大肌和腹直肌鞘皮瓣重建、长期使用抗生素和充分引流的方法,是心脏手术后深部胸骨伤口感染重建的有益技术。引流管使用时间可能是住院时间或伤口愈合的一个指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a91/9615267/88c6828af944/IWJ-19-1829-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a91/9615267/88c6828af944/IWJ-19-1829-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a91/9615267/88c6828af944/IWJ-19-1829-g001.jpg

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Turk Gogus Kalp Damar Cerrahisi Derg. 2019 Jan 1;27(1):15-22. doi: 10.5606/tgkdc.dergisi.2019.15659. eCollection 2019 Jan.
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Deep sternal wound infection following cardiac surgery: A comparison of the monolateral with the bilateral pectoralis major flaps.心脏手术后胸骨深部伤口感染:单蒂与双蒂胸大肌皮瓣的比较。
Int Wound J. 2020 Jun;17(3):683-691. doi: 10.1111/iwj.13324. Epub 2020 Feb 17.
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Benefits may not outweigh risks of low molecular weight heparin (LMWH) in early postoperative thromboprophylaxis following minimally invasive cardiac surgery: a propensity score-matched analysis.
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The Effect of Ultrasound-Assisted Debridement Combined with Vacuum Pump Therapy in Deep Sternal Wound Infections.超声辅助清创联合真空泵治疗对深部胸骨伤口感染的影响
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