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血管内支架置入术对创伤性锁骨下动脉损伤患者预后的影响

Impact of Endovascular Stenting on Outcomes in Patients with Traumatic Subclavian Artery Injury.

作者信息

Zambetti Benjamin R, Stuber Jacqueline D, Patel Devanshi D, Lewis Richard H, Huang Dih-Dih, Zickler William P, Fischer Peter E, Magnotti Arianna L, Croce Martin A, Magnotti Louis J

机构信息

From the Department of Surgery, University of Tennessee Health Science Center (Zambetti, Stuber, Patel, Lewis, Huang, Zickler, Fischer, Magnotti, Croce, Magnotti).

出版信息

J Am Coll Surg. 2022 Apr 1;234(4):444-449. doi: 10.1097/XCS.0000000000000077.

Abstract

BACKGROUND

Traumatic subclavian artery injury (SAI) remains uncommon but can lead to significant morbidity and mortality. Although open and endovascular repair offer excellent limb salvage rates, their role in blunt and penetrating injuries is not well defined. The goal of this study was to examine the effect of mechanism of injury and type of repair on outcomes in patients with traumatic SAI.

STUDY DESIGN

Patients undergoing procedures for traumatic SAI were identified from the Trauma Quality Improvement Program database between 2015 and 2018. Demographics, severity of injury and shock, type of subclavian repair (open vs endovascular), morbidity, and mortality were recorded. Patients with SAI were stratified by mechanism and type of repair and compared. Multivariable logistic regression (MLR) analysis was performed to determine independent predictors of mortality.

RESULTS

Seven hundred thirty-seven patients undergoing procedures for SAI were identified. Of these, 39% were penetrating. The majority were male (80%) with a median age and Injury Severity Score (ISS) of 37 and 21, respectively. 58% of patients were managed endovascularly. For patients with blunt injury, the type of repair affected neither morbidity (25% vs 19%, p = 0.116) nor mortality (11% vs 10%, p = 0.70). For patients with penetrating injuries, endovascular repair had significantly lower morbidity (12% vs 22%, p = 0.028) and mortality (6% vs 21%, p = 0.001). MLR identified endovascular repair as the only modifiable risk factor associated with reduced mortality (odds ratio, 0.35; 95% confidence interval, 0.14 to 0.87, p = 0.02).

CONCLUSIONS

SAI results in significant morbidity and mortality regardless of mechanism. Although the type of repair did not affect mortality in patients with blunt injury, endovascular repair was identified as the only modifiable predictor of reduced mortality in patients with penetrating injuries.

摘要

背景

创伤性锁骨下动脉损伤(SAI)虽仍不常见,但可导致严重的发病率和死亡率。尽管开放修复和血管腔内修复能提供出色的肢体挽救率,但其在钝性和穿透性损伤中的作用尚不明确。本研究的目的是探讨损伤机制和修复类型对创伤性SAI患者预后的影响。

研究设计

从2015年至2018年的创伤质量改进计划数据库中识别接受创伤性SAI手术的患者。记录人口统计学资料、损伤和休克的严重程度、锁骨下修复类型(开放修复与血管腔内修复)、发病率和死亡率。SAI患者按损伤机制和修复类型进行分层并比较。进行多变量逻辑回归(MLR)分析以确定死亡率的独立预测因素。

结果

共识别出737例接受SAI手术的患者。其中,39%为穿透性损伤。大多数患者为男性(80%),中位年龄和损伤严重程度评分(ISS)分别为37和21。58%的患者接受了血管腔内治疗。对于钝性损伤患者,修复类型对发病率(25%对19%,p = 0.116)和死亡率(11%对10%,p = 0.70)均无影响。对于穿透性损伤患者,血管腔内修复的发病率(12%对22%,p = 0.028)和死亡率(6%对21%,p = 0.001)显著更低。MLR确定血管腔内修复是与降低死亡率相关的唯一可改变风险因素(比值比,0.35;95%置信区间,0.14至0.87,p = 0.02)。

结论

无论损伤机制如何,SAI都会导致严重的发病率和死亡率。尽管修复类型对钝性损伤患者的死亡率没有影响,但血管腔内修复被确定为穿透性损伤患者死亡率降低的唯一可改变预测因素。

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