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青少年血管损伤介入治疗与开放修复治疗比较:血管入路困难患者。

Endovascular Versus Open Repair in Adolescent Patients With Difficult-to-Access Vascular Injuries.

机构信息

Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona.

Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona.

出版信息

J Surg Res. 2024 Oct;302:385-392. doi: 10.1016/j.jss.2024.07.068. Epub 2024 Aug 16.

Abstract

INTRODUCTION

Management of subclavian artery injuries (SAI) and iliac artery injuries (IAI) in adolescent trauma patients poses a considerable challenge due to their complex anatomical locations. The aim of our study was to determine the association between the injury mechanism and type of repair with the outcomes of patients with traumatic SAI and IAI.

METHODS

In this retrospective analysis of the American College of Surgeons Trauma Quality Improvement Program database2017-2020, adolescent (<18 y) patients with SAI and IAI undergoing either endovascular or open repair were included. Patients were stratified by mechanism (blunt versus penetrating) and type of repair (endovascular [E] versus open [O]) and compared. Outcomes measured were mortality and major complications. Multivariable logistic regression analyses were performed.

RESULTS

Over 4 y, 170 pediatric patients were identified, of which 73 (43%) sustained an SAI and 97 (57%) had IAI. The mean age was 15 and 79% were male. Overall, 39% were managed endovascularly. Both groups had comparable median injury severity score (E: 23 versus O: 25, P = 0.278). For patients with blunt injury (n = 60), the type of repair was neither associated with major complications (E: 39% versus O: 33%, P = 0.694) nor mortality (E: 2.6% versus O: 4.8%, P = 0.651). For patients with penetrating injuries (n = 110), the endovascular repair had significantly lower morbidity (19% versus 41%, P = 0.034) and mortality (3.7% versus 21%, P = 0.041). On multivariable logistic regression, endovascular repair was identified as the only modifiable risk factor associated with reduced mortality (adjusted odds ratio: 0.201, 95% confidence interval [0.14-0.76], P = 0.038).

CONCLUSIONS

Difficult-to-access vascular injuries result in significant morbidity and mortality. Endovascular repair was found to be the only modifiable factor associated with decreased mortality of patients with penetrating injury, whereas the type of repair was not associated with mortality in those with blunt injury.

摘要

介绍

在青少年创伤患者中,锁骨下动脉损伤(SAI)和髂动脉损伤(IAI)的管理具有相当大的挑战性,因为它们的解剖位置复杂。我们的研究旨在确定损伤机制和修复类型与创伤性 SAI 和 IAI 患者的结果之间的关系。

方法

在 2017-2020 年美国外科医师学会创伤质量改进计划数据库的这项回顾性分析中,纳入了接受血管内或开放修复的青少年(<18 岁)SAI 和 IAI 患者。根据机制(钝性与穿透性)和修复类型(血管内[E]与开放[O])对患者进行分层,并进行比较。测量的结果是死亡率和主要并发症。进行多变量逻辑回归分析。

结果

在 4 年期间,确定了 170 名儿科患者,其中 73 名(43%)患有 SAI,97 名(57%)患有 IAI。平均年龄为 15 岁,79%为男性。总体而言,39%的患者接受了血管内治疗。两组的损伤严重程度评分中位数相似(E:23 对 O:25,P=0.278)。对于钝性损伤患者(n=60),修复类型与主要并发症(E:39%对 O:33%,P=0.694)或死亡率(E:2.6%对 O:4.8%,P=0.651)均无相关性。对于穿透性损伤患者(n=110),血管内修复的发病率显著降低(19%对 41%,P=0.034),死亡率也显著降低(3.7%对 21%,P=0.041)。多变量逻辑回归分析显示,血管内修复是唯一与降低死亡率相关的可改变的危险因素(调整后的优势比:0.201,95%置信区间[0.14-0.76],P=0.038)。

结论

难以接近的血管损伤会导致显著的发病率和死亡率。血管内修复被发现是与穿透性损伤患者死亡率降低相关的唯一可改变的因素,而在钝性损伤患者中,修复类型与死亡率无关。

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