Opt Lett. 2022 Mar 15;47(6):1462-1465. doi: 10.1364/OL.452229.
Photoacoustic imaging with optical resolution usually requires a single-pixel raster scan. An alternative approach based on illumination with patterns obtained from a Hadamard matrix, measurement of the generated ultrasound wave with a single detector, followed by a reconstruction known from computational ghost imaging is demonstrated here. Since many pixels on the object are illuminated at the same time, thereby contributing to the recorded signal, this approach gives a better contrast-to-noise ratio compared to the raster scan, as demonstrated in a phantom experiment. Furthermore, exploiting the temporal information for depth-resolved imaging is possible. The proposed method will be beneficial in situations where the radiant exposure of a sample is limited due to either safety precautions or the properties of the available light source.
光声成像是一种常用的医学影像技术，它可以利用光声效应来获取生物组织的高分辨率图像。本文提出了一种基于哈达玛矩阵的光声成像方法，该方法不需要进行逐点扫描，而是通过对物体进行图案照明，利用单个探测器测量产生的超声波，然后通过计算幽灵成像中的重建算法来获取图像。由于物体上的许多像素同时被照亮，从而对记录的信号做出贡献，因此与逐点扫描相比，这种方法具有更好的对比度噪声比，这在体模实验中得到了验证。此外，还可以利用时间信息进行深度分辨成像。该方法在由于安全措施或可用光源的性质而限制样品辐射暴露的情况下将非常有用。
