Sorbonne University, Brain and Spine Institute, INSERM UMR_S 1127/UMR 7225, 57 boulevard de l'hôpital, 75013 Paris, France; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France.
AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
Psychiatry Res. 2022 May;311:114498. doi: 10.1016/j.psychres.2022.114498. Epub 2022 Mar 9.
Autism spectrum disorder (ASD) is a very heterogeneous disorder. Obsessive compulsive disorder (OCD) comorbidity, frequent in ASD, could be useful to define a specific ASD subtype. Our objective was to explore if adults with ASD and comorbid OCD could present a specific clinical profile of ASD in 89 high functioning-adult ASD patients. We found that adults with ASD and comorbid OCD showed a lower verbal IQ and a more severe impairments in social cognition. ASD with comorbid OCD present a specific clinical profile which could constitute a possible subtype of ASD.
自闭症谱系障碍（ASD）是一种非常异质的疾病。强迫症（OCD）共病在 ASD 中很常见，这可能有助于定义特定的 ASD 亚型。我们的目的是在 89 名高功能 ASD 成年患者中探索 ASD 合并强迫症的成年人是否具有特定的 ASD 临床特征。我们发现，ASD 合并强迫症的成年人表现出较低的言语智商和更严重的社会认知障碍。ASD 合并强迫症具有特定的临床特征，这可能构成 ASD 的一种可能亚型。
