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在社区成年人样本中考察强迫症和自闭症谱系障碍症状之间的相关性。

Examining the correlation between symptoms of obsessive compulsive disorder and autism spectrum disorder in a community-based sample of adults.

机构信息

Associate Professor, Special Education and Multiple Abilities, University of Alabama, Box 870232, Tuscaloosa, AL 35487, USA.

Associate Professor, Special Education and Multiple Abilities, University of Alabama, Box 870232, Tuscaloosa, AL 35487, USA.

出版信息

Psychiatry Res. 2021 May;299:113826. doi: 10.1016/j.psychres.2021.113826. Epub 2021 Feb 24.

Abstract

We examined the association between obsessive compulsive disorder (OCD) and autism spectrum disorder (ASD) symptoms among a community-based sample of adults (n = 217) that completed an OCD and ASD screening instrument. Approximately 39% of the sample that met the ASD screener cutoff criteria also met the screener cutoff criteria for OCD. The correlation between overall OCD symptoms (i.e., obsessions and compulsions) and ASD symptoms was small but statistically significant for the entire sample of participants. Similarly, obsession and compulsion subscales showed almost identical results for correlation with ASD symptoms (i.e., small but statistically significant) for the entire sample. These results suggest that levels of compulsions and obsessions are equally correlated with ASD symptoms, and neither elevated compulsions nor obsessions differentially predicted the severity of ASD symptoms in a community-based sample of adults. However, when the analysis was restricted to only the participants that met screening criteria cutoff score for ASD, statistically significant results occurred with only elevated compulsions accurately predicting severity of ASD symptoms. These results suggest that compulsive behavior appears to be a good candidate for targeting intervention resources for individuals with characteristics of ASD given the mounting data suggesting that compulsions are more common than obsessions.

摘要

我们在一个基于社区的成年人样本中(n=217),对强迫症(OCD)和自闭症谱系障碍(ASD)症状之间的关联进行了检查,该样本完成了 OCD 和 ASD 筛查工具。大约 39%的符合 ASD 筛查截止标准的样本也符合 OCD 筛查截止标准。在整个参与者样本中,总体 OCD 症状(即强迫观念和强迫行为)与 ASD 症状之间的相关性很小,但具有统计学意义。同样,对于整个样本,强迫观念和强迫行为子量表与 ASD 症状的相关性也几乎相同(即,很小但具有统计学意义)。这些结果表明,强迫行为和强迫观念的程度与 ASD 症状同样相关,而且在社区成年人样本中,无论是强迫行为还是强迫观念升高都不能预测 ASD 症状的严重程度。然而,当分析仅限于仅符合 ASD 筛查标准截止分数的参与者时,仅升高的强迫行为准确预测了 ASD 症状的严重程度,这才出现具有统计学意义的结果。这些结果表明,鉴于越来越多的数据表明强迫行为比强迫观念更为常见,强迫行为似乎是针对具有 ASD 特征的个体的干预资源的一个很好的候选目标。

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