Vivek Babu B, Smiline Girija A S, Vijayashree Priyadharsini J
Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai - 600077, India.
Bioinformation. 2021 Dec 31;17(12):1109-1112. doi: 10.6026/973206300171109. eCollection 2021.
Oral pathogens have created a menace in recent years due to biofilm formation and antimicrobial drug resistance. The current treatment strategy works well with antibiotics. However, constant use of antibiotics creates a selective pressure, which increases adaptability of the pathogens. Therefore, it is of interest to analyze the potential targets of genistein in dental pathogens using computer aided prediction tools.
近年来,口腔病原体由于生物膜形成和抗微生物药物耐药性而构成了一种威胁。目前的治疗策略使用抗生素效果良好。然而,持续使用抗生素会产生选择性压力,这会增加病原体的适应性。因此,利用计算机辅助预测工具分析金雀异黄素在口腔病原体中的潜在靶点是很有意义的。