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良性转移性平滑肌瘤继发脊髓压迫症

Spinal Cord Compression Secondary to Benign Metastasizing Leiomyoma.

作者信息

Ferreira André, Malheiro Mariana, Martins Ana

机构信息

Medical Oncology, Hospital de São Francisco Xavier, Lisbon, PRT.

Medical Oncology, Hospital CUF Tejo, Lisbon, PRT.

出版信息

Cureus. 2022 Feb 2;14(2):e21845. doi: 10.7759/cureus.21845. eCollection 2022 Feb.

Abstract

Benign metastasizing leiomyoma is an extremely rare disease characterized by the presence of extrauterine spread of smooth muscle cells with histological, molecular, and immunological patterns similar to those of benign uterine leiomyomas. Benign metastasizing leiomyoma is often asymptomatic, and it presents as an incidental radiology finding of well-defined multiple pulmonary nodules with varying sizes. It is more frequent in premenopausal women, and a previous history of uterine leiomyomas resected in the past is found in most of the cases. There are very few case reports of benign metastasizing leiomyoma causing spinal cord compression. The authors report an uncommon case of a premenopausal woman with spinal cord compression one year after the diagnosis of benign metastasizing leiomyoma to the lung. Given that spinal cord compression is an oncologic neurosurgical emergency, rapid diagnosis and management are essential to prevent irreversible neurological deficits.

摘要

良性转移性平滑肌瘤是一种极为罕见的疾病,其特征是子宫外存在平滑肌细胞扩散,组织学、分子学和免疫学模式与良性子宫平滑肌瘤相似。良性转移性平滑肌瘤通常无症状,表现为偶然通过影像学发现的边界清晰、大小不一的多个肺结节。它在绝经前女性中更为常见,大多数病例有既往子宫平滑肌瘤切除史。良性转移性平滑肌瘤导致脊髓压迫的病例报告非常少。作者报告了一例罕见病例,一名绝经前女性在被诊断为肺良性转移性平滑肌瘤一年后出现脊髓压迫。鉴于脊髓压迫是一种肿瘤神经外科急症,快速诊断和处理对于预防不可逆的神经功能缺损至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a083/8896877/5b1a39b410fd/cureus-0014-00000021845-i01.jpg

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