Meddeb Mariam, Chow Robert D, Whipps Randolph, Haque Reyaz
Departments of Cardiology and Internal Medicine, University of Maryland Midtown Campus, University of Maryland Medical System, Baltimore, MD, USA.
Case Rep Cardiol. 2018 May 21;2018:7231326. doi: 10.1155/2018/7231326. eCollection 2018.
Uterine leiomyomas are the most common gynecological tumors in premenopausal women. While the lung is the most common extrauterine organ afflicted, benign metastasizing leiomyomas (BML) of the heart are rarities. We report an incidental finding of a cardiac mass in a 36-year-old woman who presented to the Emergency Department after a motor vehicle accident. CT scan of the chest revealed 2 well-circumscribed pulmonary nodules and a filling defect in the right ventricle. Echocardiogram showed a 4 cm mass attached to the right ventricular (RV) septum. The cardiac tumor was resected and showed benign histologic features. Immunohistochemical staining was positive for smooth muscle -actin and desmin, as well as estrogen and progesterone receptors, consistent with the diagnosis of uterine leiomyoma.
子宫平滑肌瘤是绝经前女性最常见的妇科肿瘤。虽然肺部是最常受累的宫外器官，但心脏的良性转移性平滑肌瘤（BML）却很罕见。我们报告了一例36岁女性的心脏肿物偶然发现病例，该女性在机动车事故后被送往急诊科。胸部CT扫描显示2个边界清晰的肺结节以及右心室充盈缺损。超声心动图显示一个4厘米大小的肿物附着于右心室（RV）间隔。心脏肿瘤被切除，组织学特征显示为良性。免疫组化染色平滑肌肌动蛋白、结蛋白以及雌激素和孕激素受体均呈阳性，符合子宫平滑肌瘤的诊断。
