College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Division of Otolaryngology, University of Utah, Salt Lake City, UT, USA.
Acta Neurochir (Wien). 2022 Jul;164(7):1949-1952. doi: 10.1007/s00701-022-05178-x. Epub 2022 Mar 16.
Olfactory neuroblastoma, also known as esthesioneuroblastoma, accounts for only 3-6% of sinonasal malignancies but confers a 40% 5-year overall survival.
The authors describe techniques for the endonasal, minimally invasive resection of an esthesioneuroblastoma in a 69-year-old man who presented with headaches and anosmia and describe surgical nuances and their effect on adjuvant therapy planning.
This approach, along with microsurgical techniques, helped increase tumor visualization, improved marginal resection, and reduced surgical risk, which may improve patient outcomes. Multilayered reconstruction with a synthetic dural substitute and creation of a nasoseptal flap were performed to reduce postoperative cerebrospinal fluid leak.
嗅神经母细胞瘤，又称嗅神经上皮瘤，仅占鼻腔鼻窦恶性肿瘤的 3-6%，但 5 年总生存率为 40%。
作者描述了一种经鼻内镜微创手术切除嗅神经母细胞瘤的技术，该技术应用于一位 69 岁的男性患者，该患者表现为头痛和嗅觉丧失，并描述了手术细节及其对辅助治疗计划的影响。
这种方法与显微外科技术一起，有助于增加肿瘤可视化，改善边缘切除，降低手术风险，从而可能改善患者的预后。使用合成硬脑膜替代品进行多层重建和鼻中隔瓣的创建，以减少术后脑脊液漏。
