Universidade Federal do Paraná, Hospital de Clínicas, Departamento Medicina Interna, Curitiba PR, Brazil.
Instituto de Neurologia de Curitiba, Pesquisa Clínica, Curitiba PR, Brazil.
Arq Neuropsiquiatr. 2022 May;80(5):539-542. doi: 10.1590/0004-282X-ANP-2021-0298.
Professor Sérgio Mascarenhas was a Brazilian researcher with a vast legacy. His work paved the way for new research possibilities by consolidating the use of innovation and transdisciplinary science. In Medicine, he proposed changes to what had previously been well-accepted concepts, and his contributions have influenced medical practices. Although many authors consider intracranial pressure (ICP) as an unrivaled variable for monitoring and diagnosis of many diseases, its clinical applicability is still the subject of debate in the literature because of the difficulty in standardizing protocols. Mascarenhas's research and the creation of a device for noninvasive monitoring of intracranial compliance are discussed and are shown to have led to the creation of Brain4care, a start-up, and a new perspective on the debate on ICP monitoring.
塞尔吉奥·马卡森哈斯教授是一位巴西研究员，他留下了丰富的遗产。他的工作通过巩固创新和跨学科科学的应用，为新的研究可能性铺平了道路。在医学领域，他提出了改变先前被广泛接受的概念的建议，他的贡献影响了医学实践。尽管许多作者认为颅内压（ICP）是监测和诊断许多疾病的无与伦比的变量，但由于难以标准化协议，其临床适用性在文献中仍存在争议。本文讨论了马卡森哈斯的研究和用于非侵入性监测颅内顺应性的设备的创建，并表明这导致了 Brain4care 的创建，这是一个新的创业公司，也是对 ICP 监测争议的一个新视角。
