Vector Psychometric Group, LLC, Chapel Hill, North Carolina, USA.
Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
Headache. 2022 Mar;62(3):284-293. doi: 10.1111/head.14274. Epub 2022 Mar 16.
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health crisis that has had a range of impacts on people living with migraine.
Qualitative interviews performed as part of the Migraine Clinical Outcome Assessment System project, a multi-stage Food and Drug Administration-grant funded program to develop a patient-centered core set of outcome measures for use in migraine clinical trials, offered an opportunity to explore the experience of living with migraine during the pandemic as well as to examine whether migraine treatment priorities, symptoms, and associated disability changed due to the pandemic. Semi-structured interviews were conducted in the United States between the summer and fall of 2020 with 40 individuals with self-reported, medically diagnosed migraine who self-reported that they had not tested positive for or been diagnosed with COVID-19.
Seventy percent (n = 28) of the sample reported ≥1 pandemic-related impact on their life with migraine. Fourteen participants reported both positive and negative impacts, twelve reported negative impacts only, and two reported positive impacts only. Among those reporting ≥1 pandemic-related impact, nine participants (32%) reported more frequent and five (17%) reported less frequent migraine attacks. Other negative impacts included interrupted medical care (n = 9; 32%), and greater stress (n = 13; 46%). The most frequent positive impact reported was greater access to health care (n = 8; 29%). Ictal and interictal symptoms were not noted to change due to the pandemic, but some respondents reported less disability due to increased flexibility of schedules and reduced expectations. Treatment priorities did not change due to the pandemic.
The global COVID-19 pandemic has resulted in both negative and positive impacts for people living with migraine. Lessons to be considered when moving into a post-pandemic world include benefits of and satisfaction with telehealth and the benefits and importance of healthy lifestyle habits and flexibility such as improved sleep, reduced stress, and fewer social expectations.
2019 年冠状病毒病（COVID-19）大流行是一场持续的全球卫生危机，对偏头痛患者产生了一系列影响。
作为食品和药物管理局资助的多阶段项目——偏头痛临床结局评估系统项目的一部分进行的定性访谈，该项目旨在开发用于偏头痛临床试验的以患者为中心的核心结局测量集，为探索大流行期间偏头痛患者的生活体验以及检查偏头痛治疗重点、症状和相关残疾是否因大流行而改变提供了机会。2020 年夏秋季，在美国对 40 名自我报告患有经医学诊断的偏头痛且自我报告未检测出或未被诊断出 COVID-19 的个体进行了半结构化访谈。
样本中 70%（n=28）的人报告其偏头痛生活受到至少 1 个大流行相关影响。14 名参与者报告了积极和消极影响，12 名报告了消极影响，2 名报告了积极影响。在报告≥1 个大流行相关影响的参与者中，9 名（32%）报告偏头痛发作更频繁，5 名（17%）报告偏头痛发作更不频繁。其他负面影响包括医疗中断（n=9；32%）和更大压力（n=13；46%）。报告最多的积极影响是更方便获得医疗保健（n=8；29%）。由于大流行，发作期和发作间期症状没有变化，但一些受访者报告由于日程安排更灵活和期望降低，残疾程度降低。由于大流行，治疗重点没有改变。
全球 COVID-19 大流行对偏头痛患者产生了积极和消极影响。在进入后大流行时代时，需要考虑的经验教训包括远程医疗的益处和满意度，以及健康生活习惯和灵活性的益处和重要性，例如改善睡眠、减轻压力和减少社会期望。
