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由C群脑膜炎奈瑟菌引起并合并感染SARS-CoV-2的致命性儿童侵袭性脑膜炎球菌病:墨西哥蒂华纳一例报告

Fatal Pediatric Meningococcal Invasive Disease Caused by Neisseria meningitidis Serogroup C and Co-Infected With SARS-CoV-2: Report of a Case in Tijuana, Mexico.

作者信息

Chacón-Cruz Enrique, Lopatynsky Erika Z, Machado-Contreras Jesus R, Gatica-Herrera Ricardo, Zazueta Oscar E

机构信息

Infectología, Hospital General de Tijuana, Tijuana, MEX.

Health-State Scientific Committee, Secretaria de Salud de Baja California, Mexicali, MEX.

出版信息

Cureus. 2022 Feb 10;14(2):e22100. doi: 10.7759/cureus.22100. eCollection 2022 Feb.

DOI:10.7759/cureus.22100
PMID:35295362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8917855/
Abstract

Invasive meningococcal disease (IMD) is a severe infection caused by , with mortality rates ranging from 10% to 40%. IMD has been confirmed to be an endemic disease in Tijuana, Mexico, right across the border from San Diego, California. To date, coronavirus disease 2019 (COVID-19) is the most severe pandemic, causing more than 5.5 million deaths globally. Prior or co-infections of influenza with IMD has been reported previously; however, the participation of other respiratory viruses facilitating the invasiveness of is either not shown or remains unclear. Here, we report the case of an unvaccinated (for IMD and COVID-19) seven-year-old child who had confirmed fatal IMD caused by , serogroup C, and was co-infected by severe acute respiratory syndrome coronavirus 2.

摘要

侵袭性脑膜炎球菌病(IMD)是一种由[病原体未明确]引起的严重感染,死亡率在10%至40%之间。IMD已被确认为墨西哥蒂华纳的一种地方病,该地与加利福尼亚州圣地亚哥仅隔着边境。迄今为止,2019冠状病毒病(COVID-19)是最严重的大流行病,在全球造成了超过550万人死亡。此前曾有流感与IMD合并感染的报道;然而,其他呼吸道病毒在促进[病原体未明确]侵袭性方面的作用要么未被证实,要么仍不清楚。在此,我们报告一例未接种(针对IMD和COVID-19)疫苗的7岁儿童病例,该儿童确诊因C群[病原体未明确]导致致命的IMD,并同时感染了严重急性呼吸综合征冠状病毒2。

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