Ribolsi Michele, Fiori Nastro Federico, Pelle Martina, Medici Caterina, Sacchetto Silvia, Lisi Giulia, Riccioni Assia, Siracusano Martina, Mazzone Luigi, Di Lorenzo Giorgio
Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, Rome, Italy.
Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Front Psychiatry. 2022 Feb 28;13:768586. doi: 10.3389/fpsyt.2022.768586. eCollection 2022.
There is strong evidence for the existence of a high comorbidity between autism and psychosis with percentages reaching up to 34. 8% and several significant implications for treatment and prognosis of these patients. However, the identification of comorbid psychosis in patients with Autism Spectrum Disorder represents a complex challenge from a psychopathological point of view, in particular in patients with greater deficits in verbal communication. Intercepting the onset of a psychotic breakdown in autism may be very difficult, both disorders in fact occur along a phenotypic continuum of clinical severity and in many cases, psychotic symptoms are present in an attenuated form. In this paper, we reviewed the available scientific literature about comorbidity between psychosis and autism, focusing our attention on four specific dimensions: delusions, hallucinations, negative symptoms, and clinical course. The aim of this paper is to provide clinical tools to identify these psychotic phenomena in autistic patients, even when they occur in their attenuated form.
有充分证据表明自闭症与精神病之间存在高度共病性,其百分比高达34.8%,并且对这些患者的治疗和预后有若干重大影响。然而,从精神病理学角度来看,在自闭症谱系障碍患者中识别共病性精神病是一项复杂的挑战,尤其是在言语交流方面有较大缺陷的患者中。在自闭症中截获精神病发作可能非常困难,事实上这两种疾病都沿着临床严重程度的表型连续体发生,而且在许多情况下,精神病症状以减弱的形式出现。在本文中,我们回顾了关于精神病与自闭症共病性的现有科学文献,将注意力集中在四个特定维度上:妄想、幻觉、阴性症状和临床病程。本文的目的是提供临床工具,以识别自闭症患者中的这些精神病现象,即使它们以减弱的形式出现。