[Microenvironment in Hepatocellular Carcinoma].

Recently, single cell gene expression analysis was performed to help understand the complexity of cell populations. Single- cell analysis can analyze the diversity of individual cell populations as well as the tissue microenvironment, and is extremely useful for research on intercellular interactions in diseases and identifying specific marker genes. Recent advances in technology have made it possible to analyze hundreds of single cells in many cancer tissues, including stromal cells. In this paper, we introduce research examples of hepatocellular carcinoma by single cell transcriptome analysis.