Fräki J E, Schechter N M, Lazarus G S
Arch Dermatol Res. 1986;278(5):363-6. doi: 10.1007/BF00418163.
The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.
人皮肤的主要糜蛋白酶和胰蛋白酶在人真皮的高盐提取物中被发现。与来自同一患者的受累皮肤提取物、人皮肤血管瘤以及正常人皮肤提取物中的水平相比，这些酶的水平在人皮肤肥大细胞增多症的盐提取物中显著升高。这些数据表明，人皮肤的糜蛋白酶和胰蛋白酶主要起源于肥大细胞。
