Yang Ping, Wang Min, Luo Cimei, Ni Xuejin, Li Ling
Key Laboratory of Basic Psychological and Cognitive Neuroscience, School of Psychology, Guizhou Normal University, Guiyang, 550025, China.
Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Exp Brain Res. 2022 May;240(5):1445-1457. doi: 10.1007/s00221-022-06344-4. Epub 2022 Mar 17.
According to the spatial congruency advantage, individuals exhibit higher accuracy and shorter reaction times during the visual working memory (VWM) task when VWM test stimuli appear in spatially congruent locations, relative to spatially incongruent locations, during the encoding phase. Functional magnetic resonance imaging studies have revealed changes in right inferior frontal gyrus (rIFG) and right supra-marginal gyrus (rSMG) activity as a function of object location stability. Nevertheless, it remains unclear whether these regions play a role in active object location repositioning or passive early perception of object location stability, and demonstrations of causality are lacking. In this study, we adopted an object identity change-detection task, involving a short train of 10-Hz online repetitive transcranial magnetic stimulations (rTMS) applied at the rIFG or rSMG concurrently with the onset of VWM test stimuli. In two experimental cohorts, we observed an improved accuracy in spatially incongruent high VWM load conditions when the 10 Hz-rTMS was applied at the rIFG compared with that in TMS control conditions, whereas these modulatory effects were not observed for the rSMG. Our results suggest that the rIFG and rSMG play dissociable roles in the spatial congruency effect, whereby the rIFG is engaged in active object location repositioning, while the rSMG is engaged in passive early perception of object location stability.
根据空间一致性优势，在视觉工作记忆（VWM）任务中，当VWM测试刺激在编码阶段出现在空间一致的位置而非空间不一致的位置时，个体表现出更高的准确性和更短的反应时间。功能磁共振成像研究已经揭示了右下额叶回（rIFG）和右缘上回（rSMG）的活动变化与物体位置稳定性的关系。然而，尚不清楚这些区域在主动的物体位置重新定位或对物体位置稳定性的被动早期感知中是否起作用，且缺乏因果关系的证明。在本研究中，我们采用了物体身份变化检测任务，在VWM测试刺激开始时，对rIFG或rSMG施加一列短的10赫兹在线重复经颅磁刺激（rTMS）。在两个实验队列中，我们观察到，与经颅磁刺激对照条件相比，当在rIFG施加10赫兹rTMS时，在空间不一致的高VWM负荷条件下准确性提高，而在rSMG未观察到这些调节作用。我们的结果表明，rIFG和rSMG在空间一致性效应中发挥不同的作用，其中rIFG参与主动的物体位置重新定位，而rSMG参与对物体位置稳定性的被动早期感知。
