Nuutinen J, Kunnas K, Seppä J, Kärjä J, Kolonen S
Arch Otorhinolaryngol. 1986;243(3):194-6. doi: 10.1007/BF00470620.
We cultured the adenoid tissues of 72 children with recurrent respiratory infections for fungal organisms. We also took fungal cultures of nasopharyngeal secretions from 20 healthy children and 13 healthy adults as controls. Culture for fungi were positive in 15% of the patients, in 15% of the healthy adults and in 25% of the healthy children. Candida albicans, C. parapsilosis, C. tropicalis and Aspergillus sp. were the most common organisms found. In studying the children with recurrent respiratory infections, we were unable to find any significant correlation between the positive cultures and the age, type of day-care and previous antibiotic therapy given. We then studied the hemagglutination titers against C. albicans in 44 patients. This titer was 1:160 or lower in all but three patients, and was 1:320 in these latter three patients. However, fungal cultures were negative in all patients having hemagglutination titers of 1:80 or more.
我们对72名反复呼吸道感染儿童的腺样体组织进行了真菌培养。我们还对20名健康儿童和13名健康成人的鼻咽分泌物进行真菌培养作为对照。患者中15%、健康成人中15%以及健康儿童中25%的真菌培养呈阳性。白色念珠菌、近平滑念珠菌、热带念珠菌和曲霉属是最常见的检出菌。在研究反复呼吸道感染的儿童时，我们未能发现培养阳性与年龄、日托类型和既往抗生素治疗之间存在任何显著相关性。然后我们研究了44例患者针对白色念珠菌的血凝滴度。除3例患者外，其他所有患者的该滴度均为1:160或更低，而后3例患者的滴度为1:320。然而，血凝滴度为1:80或更高的所有患者真菌培养均为阴性。
