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接触力感应导管行高功率房颤消融的可行性和安全性:基于消融灶大小指数的指导消融。

Feasibility and safety of high-power ablation of atrial fibrillation with contact force-sensing catheter: The lesion size index-guided ablation.

机构信息

Charité-Universistätsmedizin Berlin, Campus Virchow Klinikum, Germany.

出版信息

Adv Clin Exp Med. 2022 Jul;31(7):715-721. doi: 10.17219/acem/146917.

Abstract

BACKGROUND

Radiofrequency (RF) ablation is a commonly used method of atrial fibrillation (AF) treatment. High-power short-duration (HPSD) ablation has been suggested as a method to reduce procedure times whilst creating safe and lasting lesions. High-power ablation with contact force (CF)-sensing technology catheters might aid in a further improvement of safety whilst generating lasting transmural lesions.

OBJECTIVES

We report our experience using lesion size index (LSI)-guided 50 W ablation with a CF-sensing catheter of AF.

MATERIAL AND METHODS

We performed LSI-guided 50 W point-by-point ablation using a CF-sensing catheter (TactiCath). Target LSI at the anterior left atrium (LA) was 5.0 and at the posterior LA it was 4.5.

RESULTS

Altogether, 4641 RF lesions were created in 86 consecutive patients. To reach a mean LSI of 4.9 ±0.01, a mean RF ablation time of 14.3 ±0.1 s was applied with a mean CF of 13.4 ±0.1 g. The RF time per lesion at the anterior wall of LA was 15.9 ±0.2 s, while it was 13 ±0.2 s at the posterior wall of LA. We observed force time integral (FTI) values between 36 g and 310 g. Procedure duration was 107 ±4 min with a RF ablation time of 15.4 ±0.6 min. No audible steam pops occurred. No pericardial effusion was observed. After a 1-year follow-up, no adverse events were reported and 83% of patients had no symptomatic arrhythmia recurrence.

CONCLUSIONS

We provide evidence for the safety and efficacy of LSI-guided 50 W ablation using the TactiCath CF-sensing ablation catheter. These data support the use of high-power ablation with CF sensing technology to improve both safety and efficacy.

摘要

背景

射频(RF)消融是治疗心房颤动(AF)的常用方法。高功率短时间(HPSD)消融已被建议用于减少手术时间,同时创建安全且持久的病变。使用具有接触力(CF)感应技术导管的高功率消融可能有助于进一步提高安全性,同时产生持久的贯穿壁病变。

目的

我们报告使用 CF 感应导管进行的基于病变大小指数(LSI)指导的 50 W 消融治疗 AF 的经验。

材料和方法

我们使用 CF 感应导管(TactiCath)进行 LSI 指导的 50 W 点到点消融。左心房(LA)前壁的目标 LSI 为 5.0,后壁的目标 LSI 为 4.5。

结果

总共在 86 例连续患者中创建了 4641 个 RF 病变。为了达到平均 LSI 为 4.9±0.01,应用了平均 14.3±0.1 s 的 RF 消融时间和平均 13.4±0.1 g 的 CF。LA 前壁每个病变的 RF 时间为 15.9±0.2 s,而 LA 后壁的 RF 时间为 13±0.2 s。我们观察到力时间积分(FTI)值在 36 g 和 310 g 之间。手术时间为 107±4 min,RF 消融时间为 15.4±0.6 min。未发生可听见的蒸汽爆裂。未观察到心包积液。在 1 年的随访中,没有发生不良事件,83%的患者没有症状性心律失常复发。

结论

我们提供了使用 TactiCath CF 感应消融导管进行 LSI 指导的 50 W 消融的安全性和有效性证据。这些数据支持使用具有 CF 感应技术的高功率消融来提高安全性和疗效。

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