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使用极短持续时间50瓦消融和接触力感应导管进行心房颤动消融。

Atrial fibrillation ablation using very short duration 50 W ablations and contact force sensing catheters.

作者信息

Winkle Roger A, Moskovitz Ryan, Hardwin Mead R, Engel Gregory, Kong Melissa H, Fleming William, Salcedo Jonathan, Patrawala Rob A, Tranter John H, Shai Isaac

机构信息

Silicon Valley Cardiology, Palo Alto Medical Foundation, Sutter Health, E. Palo Alto and Sequoia Hospital, Redwood City, CA, USA.

Silicon Valley Cardiology, 1950 University Avenue, Suite 160, E, Palo Alto, CA, 94303, USA.

出版信息

J Interv Card Electrophysiol. 2018 Jun;52(1):1-8. doi: 10.1007/s10840-018-0322-6. Epub 2018 Feb 19.

Abstract

PURPOSE

The optimal radiofrequency (RF) power and lesion duration using contact force (CF) sensing catheters for atrial fibrillation (AF) ablation are unknown. We evaluate 50 W RF power for very short durations using CF sensing catheters during AF ablation.

METHODS

We evaluated 51 patients with paroxysmal (n = 20) or persistent (n = 31) AF undergoing initial RF ablation.

RESULTS

A total of 3961 50 W RF lesions were given (average 77.6 ± 19.1/patient) for an average duration of only 11.2 ± 3.7 s. As CF increased from < 10 to > 40 g, the RF application duration decreased from 13.7 ± 4.4 to 8.6 ± 2.5 s (p < 0.0005). Impedance drops occurred in all ablations, and for patients in sinus rhythm, there was loss of pacing capture during RF delivery suggesting lesion creation. Only 3% of the ablation lesions were at < 5 g and 1% at > 40 g of force. As CF increased, the force time integral (FTI) increased from 47 ± 24 to 376 ± 102 gs (p < 0.0005) and the lesion index (LSI) increased from 4.10 ± 0.51 to 7.63 ± 0.50 (p < 0.0005). Both procedure time (101 ± 19.7 min) and total RF energy time (895 ± 258 s) were very short. For paroxysmal AF, the single procedure freedom from AF was 86% at 1 and 2 years. For persistent AF, it was 83% at 1 year and 72% at 2 years. There were no complications.

CONCLUSIONS

Short duration 50 W ablations using CF sensing catheters are safe and result in excellent long-term freedom from AF for both paroxysmal and persistent AF with short procedure times and small amounts of total RF energy delivery.

摘要

目的

使用接触力(CF)传感导管进行心房颤动(AF)消融时的最佳射频(RF)功率和损伤持续时间尚不清楚。我们评估了在AF消融期间使用CF传感导管以50W RF功率进行极短持续时间的情况。

方法

我们评估了51例接受初次RF消融的阵发性(n = 20)或持续性(n = 31)AF患者。

结果

共施加了3961个50W RF损伤(平均每位患者77.6±19.1个),平均持续时间仅为11.2±3.7秒。随着CF从<10g增加到>40g,RF施加持续时间从13.7±4.4秒减少到8.6±2.5秒(p<0.0005)。所有消融均出现阻抗下降,对于窦性心律患者,在RF输送期间出现起搏夺获丧失,提示损伤形成。仅3%的消融损伤力<5g,1%的损伤力>40g。随着CF增加,力时间积分(FTI)从47±24增加到376±102gs(p<0.0005),损伤指数(LSI)从4.10±0.51增加到7.63±0.50(p<0.0005)。手术时间(101±19.7分钟)和总RF能量时间(895±258秒)都非常短。对于阵发性AF,单次手术1年和2年时无AF的自由度分别为86%。对于持续性AF,1年时为83%,2年时为72%。无并发症发生。

结论

使用CF传感导管进行短持续时间50W消融是安全的,对于阵发性和持续性AF均可实现良好的长期无AF状态,手术时间短且总RF能量输送量小。

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