Mirro R, Gray P
Am J Perinatol. 1986 Oct;3(4):333-6. doi: 10.1055/s-2007-999891.
Newborn infants undergo major cardiovascular changes to accomplish the transition from fetal to newborn circulation. These include a drop in pulmonary vascular resistance and closure of the ductus arteriosus. We measured blood velocities by pulsed-Doppler ultrasound in the great vessels of normal newborns during this transition period. Our goals were to understand the timing of these changes and to assess cardiac function as measured by flow velocities. We concluded that shunting of blood through the ductus arteriosus continues for 1-2 days after birth without apparent hemodynamic consequences, cardiac function, as assessed by the Doppler technique, remains remarkably stable during this time period, the timing of ductal closure is not affected by the mode of delivery, and Doppler ultrasound is a portable, reproducible method which is useful in assessing the cardiovascular system of the neonate.
新生儿会经历重大的心血管变化，以完成从胎儿循环到新生儿循环的转变。这些变化包括肺血管阻力下降和动脉导管关闭。在此过渡期间，我们通过脉冲多普勒超声测量了正常新生儿大血管中的血流速度。我们的目标是了解这些变化的时间，并通过流速评估心脏功能。我们得出的结论是，出生后1至2天，通过动脉导管的血液分流仍在继续，且没有明显的血流动力学后果，在此期间，通过多普勒技术评估的心脏功能保持显著稳定，动脉导管关闭的时间不受分娩方式的影响，并且多普勒超声是一种便于携带、可重复的方法，有助于评估新生儿的心血管系统。
