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深入探究体液免疫应答 SARS-CoV-2 的(生发)中心。

Getting to the (germinal) center of humoral immune responses to SARS-CoV-2.

机构信息

Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, Australia.

Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, Australia.

出版信息

Cell. 2022 Mar 17;185(6):945-948. doi: 10.1016/j.cell.2022.02.018.

Abstract

Long-term protection against SARS-CoV-2 requires effective and durable immunity. In this issue of Cell, two papers closely examine germinal centers, the physiological birthplace of adaptive immunity, to quantify the specificity, breadth, magnitude, and persistence of systemic and local humoral immune responses following natural infection with, or vaccination against, SARS-CoV-2.

摘要

长期预防 SARS-CoV-2 需要有效的、持久的免疫力。在本期《细胞》杂志上,两篇论文密切关注生发中心,即适应性免疫的生理发源地,以量化自然感染或接种 SARS-CoV-2 疫苗后全身和局部体液免疫反应的特异性、广度、幅度和持久性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d689/8928419/9752b188ada3/gr1_lrg.jpg

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