Centre Antoine Lacassagne, Nice, France.
Centre Antoine Lacassagne, Nice, France.
Appl Radiat Isot. 2022 Jun;184:110190. doi: 10.1016/j.apradiso.2022.110190. Epub 2022 Mar 8.
A new proton beam-line dedicated to R&D programs has been developed at CentreAntoine Lacassagne (CAL), in Nice (France), in collaboration with the Centrenational d'études spatiales (CNES). This is the second beam-line of the MEDICYC 65 MeV cyclotron that is currently in operation, the first being the clinical 'eye-line' used for ocular proton therapy. The R&D beam-line is proposed with two configurations, the first producing a Gaussian narrow beam of a few mm width, the second a 100 mm diameter flat beam with a homogeneity better than ±3%. The energy range is (20 - ∼60) MeV, where the exact upper limit depends on the beam configuration being used. The energy spread of the non-degraded beam is (0.3 ± 0.1) MeV. A beam current between 10 pA and 10 μA can be produced with a stability better than 0.2% above 100 pA, and 2% below. The beam can be monitored online at a precision better than 5% in the flux range 1E5 (1E6) - 1E9 (1E10) p/cm/s for a flat (Gaussian) configuration, although work is in progress to extend this range. Targeted applications for the R&D beam-line are instrumentation research, radiation tolerance tests of components and radiobiology.
法国尼斯的 AntoineLacassagne 中心(CAL)与国家空间研究中心(CNES)合作,开发了一条新的质子束线,用于研发计划。这是正在运行的 MEDICYC65MeV 回旋加速器的第二条束线,第一条是用于眼部质子治疗的临床“视线”束线。该研发束线有两种配置,第一种可产生几毫米宽的高斯窄束,第二种可产生直径为 100mm、均匀度优于±3%的扁平束。能量范围为(20-∼60)MeV,确切的上限取决于使用的束线配置。未经退化的束线能散度为(0.3±0.1)MeV。在 100pA 以上,束流稳定性优于 0.2%,在 10pA 至 10μA 之间,可以产生束流,在 1E5(1E6)-1E9(1E10)p/cm/s 的通量范围内,在线监测精度优于 5%,适用于扁平(高斯)配置,尽管正在努力扩展此范围。研发束线的目标应用是仪器仪表研究、组件辐射耐受度测试和放射生物学。