Harvey M H, Leese T, Lloyd D, Osborn D E
Br J Urol. 1986 Aug;58(4):450-2. doi: 10.1111/j.1464-410x.1986.tb09102.x.
One hundred and sixty-two patients were studied in a random double-blind controlled trial of co-trimoxazole to prevent secondary haemorrhage following transurethral resection of the prostate (TURP). There was a significant correlation between the incidence of post-operative urinary infection and secondary haemorrhage (P less than 0.05) but no difference between the incidence of bleeding in the treatment and placebo groups. Although infection may play a role in the development of secondary haemorrhage, co-trimoxazole for 10 days does not decrease the incidence of this complication.
在一项关于复方新诺明预防经尿道前列腺切除术（TURP）后继发性出血的随机双盲对照试验中，对162例患者进行了研究。术后尿路感染发生率与继发性出血之间存在显著相关性（P<0.05），但治疗组和安慰剂组的出血发生率无差异。虽然感染可能在继发性出血的发生中起作用，但服用10天复方新诺明并不能降低这种并发症的发生率。
