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姜对行上下肢手术患者术后恶心呕吐的影响:一项随机对照试验。

The Effect of Ginger on Postoperative Nausea and Vomiting Among Patients Undergoing Upper and Lower Limb Surgery: A Randomized Controlled Trial.

机构信息

Department of Anesthesiology, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.

出版信息

J Perianesth Nurs. 2022 Jun;37(3):365-368. doi: 10.1016/j.jopan.2021.05.006. Epub 2022 Mar 15.

Abstract

PURPOSE

Postoperative nausea and vomiting is one of the most common side effects associated with anesthesia. The aim of this study is to determine the effect of ginger on severity and incidence of nausea and vomiting after lower and upper limb surgery.

DESIGN

This was a triple-blinded clinical trial.

METHODS

Sixty eligible patients were randomly assigned to the intervention and control groups. The intervention group received four 250 mg ginger capsules and the control group received four placebo capsules 2 hours before surgery. Incidence and severity of nausea and vomiting immediately after the surgery and 2, 4, 6, and 8 hours after the surgery were evaluated.

FINDINGS

The results of this study showed that the use of ginger capsules significantly reduces the incidence and severity of postoperative nausea and vomiting at different hours after surgery compared to placebo, P < .05, irrespective of the gender and the age of the patients.

CONCLUSIONS

Use of ginger is effective in decreasing postoperative nausea and vomiting. However, further studies in comorbid patients are required to verify these outcomes.

摘要

目的

术后恶心和呕吐是与麻醉相关的最常见的副作用之一。本研究旨在确定生姜对上下肢手术后恶心和呕吐的严重程度和发生率的影响。

设计

这是一项三盲临床试验。

方法

将 60 名符合条件的患者随机分配到干预组和对照组。干预组在手术前 2 小时服用 4 粒 250 毫克的生姜胶囊,对照组服用 4 粒安慰剂胶囊。评估手术后即刻以及手术后 2、4、6 和 8 小时的恶心和呕吐的发生率和严重程度。

结果

这项研究的结果表明,与安慰剂相比,生姜胶囊的使用显著降低了手术后不同时间点恶心和呕吐的发生率和严重程度,P<0.05,与患者的性别和年龄无关。

结论

使用生姜可有效减少术后恶心和呕吐。然而,需要在合并症患者中进行进一步的研究来验证这些结果。

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