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卵母细胞玻璃化冷冻用于选择性生育力保存:SWOT 分析。

Oocyte vitrification for elective fertility preservation: a SWOT analysis.

机构信息

IVI RMA Zaragoza, Zaragoza, Spain.

BrusselsIVF, Universitair Ziekenhuis Brussel, Brussels, Belgium; Department of Obstetrics and Gynaecology, University of Zagreb-School of Medicine Zagreb, Croatia.

出版信息

Reprod Biomed Online. 2022 Jun;44(6):1005-1014. doi: 10.1016/j.rbmo.2022.02.001. Epub 2022 Feb 5.

Abstract

Oocyte vitrification, also known as egg freezing, is increasingly being used by women as a precautionary measure against the anticipated decline in fertility. In countries where this procedure is allowed, elective oocyte vitrification has become an integral part of the treatment portfolio of fertility clinics. The widespread tendency towards the postponement of motherhood and the advances in laboratory technologies are encouraging women to consider oocyte vitrification and, by doing so, increase their reproductive autonomy. However, elective oocyte vitrification, or elective egg freezing (EEF), still elicits controversy, not only when EEF is appraised from a cost-efficiency point of view, but also in terms of medical and ethical concerns. In general, although the laboratory tool of vitrification has revolutionized the treatment of infertility, the pros and cons need to be clarified when considering EEF.

摘要

卵母细胞玻璃化冷冻,又称卵子冷冻,越来越多地被女性用作预防生育能力下降的一种预防措施。在允许进行这种程序的国家,选择进行卵母细胞玻璃化冷冻已成为生育诊所治疗方案的一个组成部分。推迟生育的普遍趋势和实验室技术的进步促使女性考虑卵母细胞玻璃化冷冻,并通过这种方式增加其生殖自主权。然而,选择进行卵母细胞玻璃化冷冻,即选择进行卵子冷冻(EEF),仍然存在争议,不仅在从成本效益角度评估 EEF 时如此,而且在涉及医学和伦理问题时也是如此。总的来说,尽管玻璃化冷冻这一实验室工具已经彻底改变了不孕不育的治疗方法,但在考虑 EEF 时需要明确其利弊。

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