Department of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Department of Ophthalmology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Sci Rep. 2022 Mar 18;12(1):4726. doi: 10.1038/s41598-022-08699-8.
Multi-frequency processing (MFP) leads to enhanced image quality (IQ) of radiographs. This study is to determine the effect of third generation MFP (M3) on IQ in comparison to standard second-generation MFP (M2). 20 cadavers were examined and post-processing of radiographs was performed with both M2 and M3. Three readers blinded to the MFP used for each image independently compared corresponding image pairs according to overall IQ and depiction of bony structures and soft tissue (+ 2: notably better > 0: equal > - 2: notably worse). A significant deviation of the median grade from grade 0 (equal) (p < 0.01) for each evaluator A, B and C speaks against an equal image quality of M2- and M3-images. M3-images were categorized with better grades (+ 1, + 2) in 87.7% for overall image quality, in 90.4% for soft tissue and 81.8% for bony structures. M3 images showed significant higher averaged SNR and CNR for all investigated lower extremities than that of M2 images (0.031 < p < 0.049). The newest generation of MFP leads to significantly better depiction of anatomical structures and overall image quality than in images processed with the preceding generation of MFP. This provides increased diagnostic accuracy and further decreased radiation exposure.
多频处理（MFP）可提高射线照片的图像质量（IQ）。本研究旨在比较第三代 MFP（M3）与标准第二代 MFP（M2）对 IQ 的影响。对 20 具尸体进行了检查，并对 M2 和 M3 处理后的射线照片进行了后处理。三位读者对每张图像进行了独立评估，他们根据整体 IQ 以及对骨结构和软组织的描绘（+2：明显更好>0：相等>-2：明显更差）对相应的图像对进行了比较。每个评估员 A、B 和 C 的中位数等级与等级 0（相等）的显著偏差（p<0.01）表明 M2 和 M3 图像的质量不相等。M3 图像在整体图像质量、软组织和骨结构方面分别以更好的等级（+1、+2）进行分类，达到 87.7%、90.4%和 81.8%。与 M2 图像相比，所有调查的下肢 M3 图像的平均 SNR 和 CNR 均显著更高（0.031<p<0.049）。最新一代的 MFP 可显著提高解剖结构和整体图像质量的描绘，优于前一代 MFP 处理的图像。这提供了更高的诊断准确性和进一步降低的辐射暴露。
