Kutalek S P
Cardiol Clin. 1986 Aug;4(3):473-86.
Serial pharmacologic trials guided by electrophysiologic techniques provide an objective method for instituting effective medical therapy in patients with sustained ventricular arrhythmias. Suppression of induced ventricular tachycardia by administered antiarrhythmic agents predicts the results of chronic treatment with a high degree of accuracy. Although some controversy exists with regard to precise stimulation protocols, the ability to evaluate the advantages and potentially detrimental actions of individual drugs in a controlled environment contributes substantially to the utility of electrophysiologic testing in the selection of an optimal antiarrhythmic regimen.
由电生理技术指导的系列药理学试验为对持续性室性心律失常患者实施有效的药物治疗提供了一种客观方法。给予抗心律失常药物后对诱发性室性心动过速的抑制可高度准确地预测长期治疗的结果。尽管在精确的刺激方案方面存在一些争议,但在可控环境中评估个别药物的优势和潜在有害作用的能力,在很大程度上有助于电生理检查在选择最佳抗心律失常方案中的应用。