Murphy Michael, Öngür Dost
Harvard Medical School, Boston, MA, USA.
McLean Hospital, Belmont, MA, USA.
Schizophrenia (Heidelb). 2022 Mar 18;8(1):25. doi: 10.1038/s41537-022-00238-8.
Thought disorder may be associated with subtle language abnormalities. Binomials are pairs of words of the same grammatical type that are joined by a conjunction that often have a preferred order (for example, "up and down" is more common than "down and up"). We analyzed speech transcripts from patients with first-episode psychosis and found that atypical ordering of binomial pairs was associated with thought disorder but not with other psychosis symptoms. These results illustrate the potential to generate objective, quantifiable measures of disorganized speech.
思维紊乱可能与细微的语言异常有关。二项式是由连词连接的具有相同语法类型的一对词，它们通常有一个优先顺序（例如，“上和下”比“下和上”更常见）。我们分析了首发精神病患者的言语记录，发现二项式对的非典型排序与思维紊乱有关，但与其他精神病症状无关。这些结果说明了生成客观、可量化的言语紊乱测量方法的潜力。
