Osimo Emanuele F, Brugger Stefan P, Thomas E Louise, Howes Oliver D
MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK.
Department of Psychiatry, University of Cambridge, Cambridge, UK.
Schizophrenia (Heidelb). 2022 Mar 18;8(1):24. doi: 10.1038/s41537-022-00233-z.
People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.
精神分裂症患者腹部肥胖的风险高于普通人群，这可能导致额外的死亡率。然而，目前尚不清楚这是否由腹部脂肪分布的改变所驱动。在此，我们检验了这样一个假设：使用磁共振成像（MRI）测量，精神分裂症患者的内脏脂肪占全身脂肪的比例更高。我们招募了38名精神分裂症患者和38名在年龄、性别、种族和体重指数方面相匹配的健康对照者。我们发现两组之间的体脂分布没有显著差异，这表明精神分裂症患者腹部肥胖增加与脂肪分布改变无关。
