Hoe J W, Ng A M, Tan L K
Clin Radiol. 1986 Sep;37(5):505-7. doi: 10.1016/s0009-9260(86)80080-0.
The use of iopamidol and iohexol for lumbar myelography is compared in this study. Fifty-eight patients were examined, the contrast media being allocated on a randomised double-blind basis. Radiographic quality was good with both media. Headache and an increase of back pain were the most frequent symptoms, though the incidence of side-effects was slightly but significantly greater with iohexol. We conclude from our study that while the radiographic quality is comparable, iopamidol seems to be slightly better tolerated.
本研究比较了碘帕醇和碘海醇在腰椎脊髓造影中的应用。共检查了58例患者,造影剂按随机双盲原则分配。两种造影剂的X线片质量均良好。头痛和背痛加剧是最常见的症状,不过碘海醇的副作用发生率略高,但具有显著差异。我们从研究中得出结论,虽然X线片质量相当,但碘帕醇的耐受性似乎略好。