Macpherson P, Teasdale E, Coutinho C, McGeorge A
Br J Radiol. 1985 Sep;58(693):849-51. doi: 10.1259/0007-1285-58-693-849.
A randomised double blind trial of iohexol and iopamidol in cervical myelography by both lumbar puncture and direct puncture techniques is reported in one hundred consecutive patients. All patients had EEG examination before and 6-8 h after the myelogram and for each a questionnaire regarding adverse reactions was completed at set intervals. The side effects, radiographic quality of the examination and production of sharp wave activity on EEG were equivalent in the iohexol and iopamidol series. Contrary to previous reports, we consider that iohexol and iopamidol are equally acceptable for all forms of myelography.
本文报告了一项针对100例连续患者的随机双盲试验,该试验比较了碘海醇和碘帕醇在腰椎穿刺和直接穿刺技术用于颈椎脊髓造影中的效果。所有患者在脊髓造影前和造影后6 - 8小时均接受了脑电图检查,并且在设定的时间间隔内完成了一份关于不良反应的问卷。碘海醇组和碘帕醇组在副作用、检查的放射学质量以及脑电图上出现尖波活动方面相当。与先前的报道相反,我们认为碘海醇和碘帕醇在所有形式的脊髓造影中同样适用。