Liu Juan, Wan Yanjian, Jiang Ying, Xia Wei, He Zhenyu, Xu Shunqing
Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, And State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, PR China.
Institute of Environmental Health, Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, 430024, PR China.
Environ Pollut. 2022 Jul 1;304:119168. doi: 10.1016/j.envpol.2022.119168. Epub 2022 Mar 16.
Widespread use of fungicides has raised the concern of exposure to them among the general population. However, there are extremely limited studies reporting the occurrence of fungicides in indoor dust in China. This study aimed to determine ten agricultural fungicides in indoor dust samples collected in three cities of China from 2016 to 2019, assess spatial and seasonal variations, and estimate the related exposure via dust ingestion. Six out of ten fungicides including difenoconazole, prochloraz, tebuconazole, tricyclazole, azoxystrobin, and pyraclostrobin were frequently detected in the dust samples (ranged 65.8-97.7%) and the concentrations of some fungicides showed a strong correlation with each other. Difenoconazole was the most abundant one among the selected fungicides. The highest level of the selected fungicides was observed in the indoor dust collected from Wuhan in summer 2019 (median cumulative concentration of the fungicides: 62.6 ng/g), while the relatively low concentrations of fungicides were found in the dust from Taiyuan (2.08 ng/g). Heavier fungicide contamination was observed in urban districts compared to that in rural districts. Seasonal variations in the fungicide residuals were also identified. The exposure assessment suggested that intake of the selected fungicides via dust ingestion was much lower than dietary intake reported in other studies. This study filled the data gap of fungicide residuals in the indoor dust in China and further studies are needed to identify the sources and determinants of indoor fungicide contamination.
杀菌剂的广泛使用引发了公众对其接触风险的担忧。然而，在中国，报道室内灰尘中杀菌剂存在情况的研究极为有限。本研究旨在测定2016年至2019年在中国三个城市采集的室内灰尘样本中的十种农用杀菌剂，评估其空间和季节变化，并估算通过灰尘摄入所导致的相关暴露量。在灰尘样本中，十种杀菌剂中的六种，包括苯醚甲环唑、咪鲜胺、戊唑醇、三环唑、嘧菌酯和吡唑醚菌酯，被频繁检测到（检出范围为65.8 - 97.7%），并且一些杀菌剂的浓度之间呈现出强相关性。苯醚甲环唑是所选杀菌剂中含量最高的一种。2019年夏季从武汉采集的室内灰尘中，所选杀菌剂的含量最高（杀菌剂的中位累积浓度：62.6纳克/克），而在太原的灰尘中发现的杀菌剂浓度相对较低（2.08纳克/克）。与农村地区相比，城市地区观察到更严重的杀菌剂污染。还确定了杀菌剂残留的季节变化。暴露评估表明，通过灰尘摄入所选杀菌剂的量远低于其他研究报道的饮食摄入量。本研究填补了中国室内灰尘中杀菌剂残留的数据空白，还需要进一步研究来确定室内杀菌剂污染的来源和决定因素。
