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城乡交接处的 SARS-CoV-2 传播动力学。

SARS-CoV-2 transmission dynamics in the urban-rural interface.

机构信息

Grupo de Investigación en Epidemiología y Salud Pública, Universidad de La Salle, Bogotá, Colombia.

Grupo de Investigación en Epidemiología y Salud Pública, Universidad de La Salle, Bogotá, Colombia.

出版信息

Public Health. 2022 May;206:1-4. doi: 10.1016/j.puhe.2022.02.007. Epub 2022 Feb 17.

DOI:10.1016/j.puhe.2022.02.007
PMID:35306192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8849864/
Abstract

OBJECTIVES

As the world responds to the coronavirus outbreak, the role of public health in ensuring equitable health care that considers the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dynamics in rural communities is still a challenge. The same suppression and mitigation measures have been implemented homogeneously, ignoring the differences between urban and rural areas. We propose an epidemiological model and simulate the dynamics of SARS-CoV-2 in urban and rural areas considering the interaction between these regions.

STUDY DESIGN

This was a population modeling study.

METHODS

A compartmental epidemiological model was formulated to simulate the transmission of SARS-CoV-2 in urban and rural areas. We use the model to investigate the impact of control strategies focused on the urban-rural interface to contain the epidemic size of SARS-CoV-2 in rural areas.

RESULTS

Considering five different levels for the exposition rate in urban areas and keeping intrarural and urban-rural exposition rates fixed, the preventive measures reduce the size and delay the peak for the urban infectives. The response of infected individuals and cumulative deaths in rural areas upon changes in the urban dynamics was small but not negligible. On the other hand, preventive measures focused on the urban-rural interface impact the number of infected individuals and deaths in rural areas.

CONCLUSIONS

The maintenance of SARS-CoV-2 in rural areas depends on the interaction of individuals at the urban-rural interface. Thus, restrictive measures established by the governments would not be required within rural areas. We highlight the importance of focused preventive measures on the urban-rural interface to reduce the exposure and avoid the transmission of SARS-CoV-2 to rural communities.

摘要

目的

随着世界对冠状病毒爆发的反应,公共卫生在确保公平医疗保健方面的作用仍然是一个挑战,特别是考虑到农村社区中严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)的动态变化。同样的抑制和缓解措施已经统一实施,忽略了城乡之间的差异。我们提出了一个流行病学模型,并考虑到这些地区之间的相互作用,模拟了 SARS-CoV-2 在城乡地区的动态。

研究设计

这是一项人口建模研究。

方法

我们构建了一个房室流行病学模型来模拟 SARS-CoV-2 在城乡地区的传播。我们使用该模型来研究针对城乡界面的控制策略对遏制 SARS-CoV-2 在农村地区的疫情规模的影响。

结果

考虑到城市地区暴露率的五个不同水平,并保持城乡内部和城乡之间的暴露率固定,预防措施会减少城市感染者的规模并延迟高峰。农村地区受城市动态变化影响的感染者和累积死亡人数的反应虽然较小,但并非可以忽略不计。另一方面,集中在城乡界面的预防措施会影响农村地区的感染者和死亡人数。

结论

SARS-CoV-2 在农村地区的维持取决于城乡界面个体之间的相互作用。因此,政府在农村地区不需要采取限制性措施。我们强调在城乡界面采取有针对性的预防措施的重要性,以减少暴露并避免 SARS-CoV-2 传播到农村社区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a3/8849864/1f9623dc0d9e/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a3/8849864/1f9623dc0d9e/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a3/8849864/1f9623dc0d9e/gr1_lrg.jpg

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