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cdca9 在泥鳅(Misgurnus anguillicaudatus)卵巢发育中的表达谱。

Expression profiles of cdca9 related to ovarian development in loach (Misgurnus anguillicaudatus).

机构信息

College of Fisheries, Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education/Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education/Key Lab of Freshwater Animal Breeding, Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan, China.

出版信息

J Fish Biol. 2022 May;100(5):1319-1322. doi: 10.1111/jfb.15042. Epub 2022 Apr 12.

Abstract

The function of borealin proteins has been widely reported in the cell division of animals. Nonetheless, there is little research about their only known paralogue (cell division cycle associated 9, cdca9). In this study, cdca9 was investigated in loach (Misgurnus anguillicaudatus) for the first time. cdca9 was highly expressed in the embryo before the gastrula stage, and it was predominantly expressed in the ovary, especially in the oocytes of stage II. In conclusion, this study reveals a potential function of cdca9 in the early embryogenesis and ovarian development of fish.

摘要

Borealin 蛋白的功能已在动物细胞分裂中得到广泛报道。然而,对于其唯一已知的同源物(细胞分裂周期相关蛋白 9,cdca9)的研究却很少。本研究首次对泥鳅(Misgurnus anguillicaudatus)中的 cdca9 进行了研究。cdca9 在原肠胚期之前的胚胎中高表达,主要在卵巢中表达,特别是在 II 期卵母细胞中表达。综上所述,本研究揭示了 cdca9 在鱼类早期胚胎发生和卵巢发育中的潜在功能。

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