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在南苏丹脆弱且持久的冲突状态下,儿童的常规免疫接种计划是否按部就班地进行?一项基于社区的横断面研究。

Are children on track with their routine immunization schedule in a fragile and protracted conflict state of South Sudan? A community-based cross-sectional study.

作者信息

Idris Israel Oluwaseyidayo, Tapkigen Janet, Kabutaulaka Germaine, Ayeni Gabriel Omoniyi, Ayomoh Francis Ifeanyi, Obwoya Justin Geno

机构信息

Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Department of Health Sciences, University of Tampere, Tampere, Finland.

出版信息

BMC Pediatr. 2022 Mar 21;22(1):147. doi: 10.1186/s12887-022-03213-5.

Abstract

OBJECTIVES

The objective of this study was to assess if children aged 0-23 months in a conflict-affected state of South Sudan were on track with their immunization schedule and to identify predisposing factors that affected this study population from being on track with their routine immunization schedule.

DESIGN

Community-based cross-sectional study using a semi-structured questionnaire. The binary outcome of interest was defined as being on or off track with routine vaccination schedule. Multivariable logistic regression was used to analyze for the association between the predisposing factors surveyed and being off track with one's routine immunization schedule.

SETTING

Rural communities in four counties (Rumbek Center, Rumbek North, Rumbek East and Wulu) of the Western Lakes state in South Sudan during January 10, 2020 to June 10, 2020.

PARTICIPANTS

We surveyed 428 children aged 0-23 months and their mothers/caregivers who lived in either of the four counties in the Western Lakes State. Participants were selected using random ballot sampling.

RESULTS

More than three-quarters of the children surveyed (75.5%) were off track with their vaccination schedule. Children with an immunization card had 71% reduced odds of being off track with their immunization (AOR = 0.29; 95% CI 0.10-0.83, p-value = 0.021) compared to children without immunization cards. Children who reside near health facilities and do not require transportation to facilities had 87% reduced odds of being off track with their immunization compared to those who lived far and required transport to facilities. Giving an adequate immunization notice before conducting immunization outreach visits to communities was also associated with reduced odds (AOR = 0.27; 95% CI 0.09-0.78. p-value = 0.016) of children being off track with their immunization.

CONCLUSION

This study revealed that most children were off track with their vaccination schedule in South Sudan, which is not only influenced by maternal characteristics but mainly by community- and state-level immunization service delivery mechanisms. Policies and interventions to improve child immunization uptake should prioritize these contextual characteristics.

摘要

目的

本研究的目的是评估南苏丹受冲突影响地区0至23个月大的儿童是否按免疫计划接种疫苗,并确定影响该研究人群未按常规免疫计划接种疫苗的诱发因素。

设计

采用半结构化问卷进行基于社区的横断面研究。感兴趣的二元结果定义为是否按常规疫苗接种计划接种。多变量逻辑回归用于分析所调查的诱发因素与未按常规免疫计划接种之间的关联。

地点

2020年1月10日至2020年6月10日期间,在南苏丹西湖州四个县(伦拜克中心、伦拜克北部、伦拜克东部和乌鲁)的农村社区。

参与者

我们调查了居住在西湖州四个县中任一县的428名0至23个月大的儿童及其母亲/照顾者。参与者采用随机抽签抽样选定。

结果

超过四分之三(75.5%)的被调查儿童未按疫苗接种计划接种。与没有免疫卡的儿童相比,有免疫卡的儿童未按免疫计划接种的几率降低了71%(调整后比值比[AOR]=0.29;95%置信区间[CI]为0.10 - 0.83,p值=0.021)。与居住在远处且需要前往医疗机构的儿童相比,居住在医疗机构附近且无需前往医疗机构的儿童未按免疫计划接种的几率降低了87%。在对社区进行免疫 outreach访问之前给予充分的免疫通知也与儿童未按免疫计划接种的几率降低有关(AOR = 0.27;95% CI为0.09 - 0.78,p值 = 0.016)。

结论

本研究表明,南苏丹大多数儿童未按疫苗接种计划接种,这不仅受母亲特征的影响,主要还受社区和州级免疫服务提供机制的影响。改善儿童免疫接种率的政策和干预措施应优先考虑这些背景特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c40c/8935713/825ccc390743/12887_2022_3213_Fig1_HTML.jpg

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