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认识放疗临床实践中的脆弱性:当前证据和未来方向。

Recognizing Frailty in Radiation Oncology Clinical Practice: Current Evidence and Future Directions.

机构信息

Applied Radiation Therapy Trinity and Trinity St. James's Cancer Institute, Trinity College Dublin, Ireland.

Applied Radiation Therapy Trinity and Trinity St. James's Cancer Institute, Trinity College Dublin, Ireland..

出版信息

Semin Radiat Oncol. 2022 Apr;32(2):115-124. doi: 10.1016/j.semradonc.2021.11.010.

DOI:10.1016/j.semradonc.2021.11.010
PMID:35307113
Abstract

The number of older adults presenting for radiation therapy is increasing, as many older adults may be excluded from receipt of surgery and chemotherapy due to multimorbidity or concerns about toxicity. For radiation oncologists, making decisions about appropriate treatment modalities for their older patients can be difficult. Comprehensive Geriatric Assessment (CGA) is recommended to aid the decision-making process in radiation oncology, in conjunction with the judicious use of frailty screening tools, which are the first step in identifying those who need a CGA. In this review, the current scientific evidence regarding screening tools and CGA will be appraised in the context of radiation oncology. Several screening tools that have been tested in radiation oncology are described, as well as how they have been combined (or not) with CGA. Current clinical practice is reviewed, and future directions for radiation oncology are discussed.

摘要

就诊于放疗科的老年患者人数正在增加,因为许多老年患者可能由于多种合并症或对毒性的担忧而被排除在手术和化疗之外。对于放疗科医生来说,为他们的老年患者做出合适的治疗方式决策可能很困难。推荐使用综合老年评估(CGA)来辅助放疗科的决策过程,同时明智地使用虚弱筛查工具,这是识别需要 CGA 的人的第一步。在这篇综述中,将根据放疗科的情况评估筛查工具和 CGA 的当前科学证据。描述了一些已经在放疗科中进行过测试的筛查工具,以及它们如何与 CGA 结合(或不结合)。回顾了当前的临床实践,并讨论了放疗科的未来方向。

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Integration of art and technology in personalized radiation oncology care: Experiences, evidence, and perspectives.个性化放射肿瘤学治疗中艺术与技术的融合:经验、证据和观点。
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